REFERENCE

United States Patent of Omura Yoshiaki

Patent Number: 5,188,107 Date of Patent: Feb. 23, 1993

BI-DIGITAL O-RING TEST FOR IMAGING AND DIAGNOSIS OF INTERNAL ORGANS OF A PATIENT

ABSTRACT

A method of imaging an internal organ of a patient for purposes of medical diagnosis, where a patient for purposes of medical diagnosis, where a patient forms an O-ring shape with one of hands by placing the fingertips of his thumb and one of hands by placing the fingertips of his thumb and one of his remaining fingers together and a sample of tissue of an internal organ is placed on the patient's other hand, and the patient's internal organ is non-invasively externally probed with a probing instrument. The internal organ is the same type of organ as that of the sample. Simultaneously a tester attempts to pull apart the O-ring shape by means of the tester placing his thumb and one of the remaining fingers of each of his hands within the O-ring shape of the patient to form interlocking O-rings and pulling the thumb and the finger of the patient apart due to an electromagnetic filed of the tissue of the sample interacting with an electromagnetic filed of the internal organ being probed and this interaction is detected by the ability to pull apart the O-ring shape thereby permitting imaging of the boundaries of the internal organ being probed.

B-1

CURRENT PROGRESS AND UNIQUE ADVANTAGES OF THE BI-DIGITAL O-RINGTEST AND ITS APPLICATION TO CLINICAL & BASIC MEDICINE

Yoshiaki Omura, M.D., Sc.D., F.A.C.A., F.I.C.A.E.

Director of Medical Research, Heart Disease Research Foundation, New York, USA Adjunct Prof. of Pharmacology, Chicago Medical School, Chicago, USA Visiting Research Prof., Dept. of Electrical Engineering, Manhattan College, New York, USA Adjunct Prof., Dept. of Physiology, School of Medicine, Showa University, Tokyo, Japan President, International College of Acupuncture and Electro-Therapeutics, New York, USA [Correspondence: 800 Riverside Drive (8-1), New York 10032 USA]

ABSTRACT

The Bi-Digital O-Ring Test has been successfully used in the following areas, by the application of the resonance phenomenon between two identical substances, as well as other Bi-Digital O-Ring Test techniques:

1) Early diagnosis and localization of cancer and identification of their cell types.

2) Imaging of the outline of normal and abnormal internal organs and localization of abnormal areas and their pathogenesis without using any instruments or electric devices and without exposing the body to harmful electromagnetic fields.

3) Non-invasive estimation and localization of bacterias and viruses, and other pathogenic organisms.

4) Non-invasive estimation of effective medications and their optimal dose, toxic dose, and dose response curve even before giving medication, as well as prediction of degree of drug uptake in pathological areas of the human body.

5) Non-invasive localization of circulatory disturbances by localizing Thromboxane B2.

6) Non-invasive localization of meridians and their acupuncture points and connection between meridians and organ representation areas of the cerebral cortex.

7) Non-invasive localization of organ representation areas at different parts of the body, such as the scalp, ears, tongue, hands, feet, and their application for non-invasive diagnosis and treatment of certain medical problems.

8) Non-invasive localization of neurotransmitters, hormones, drugs, metals, etc. in different parts of the human body.

9) Rapid localization of harmful electromagnetic fields, including those fields which are difficult to measure by standard electrical field meters or magnetic field meters.

10) Diagnosis, identification and localization of individualized pathogenic factors, and treatment of intractable medical problems, including amyotrophic lateral sclerosis, Alzheimer's disease, essential hypertension, intractable pain, etc.

11) Various intractable medical problems, including stroke, myocardial infarct, and cancer, are often found to correspond to prolonged repeated exposure to electro-magnetic fields coming from under the bed, particularly at the cross-sectional area of 2 electromagnetic fields.

12) Localization and classification of (+) and (-) Qi Gong energy, as well as evaluation of the Qi Gong state.

13) Evaluation of the effects of Qi Gong or application of (+) Qi Gong energy stored paper or other substances on the circulation and drug uptake.

B-2

FUTURE MEDICINE AND HUMAN SOCIETY IN BIOMATION ERA

Kazuhiko Atsumi, M.D. Emeritus, Professor, Tokyo University

ABSTRACT

The paradigms have been shifting in the various sciences of physics, chemistry, mathematics, philosophy, ecology, neuro-science, psychology, politics and also in the fields of art and religion.

The shift can be seen in the field of physics, from atomism to quantum theory, from mechanistic to holographic, from absolute to relative, from universal to complementary, and from definitive to un-definitive.

According to the paradigm shift, the quality conversion - value change - can be seen from simple to complicated and multiple, from hierachial to heterarchial, from mechanical to holographic, from defined to undefined, from linear causality to non-linear causality, from congregated to formative and from objective to subjective.

The hybridization between automation - man-made technology - and bio-organism-natural realm -, it is "Biomation". By the "Biomation", the demerits in the information society will be overcome and the mechanical civilization can sublimate up to the human civilization.

Modern trends of science and technology are classified as follows:

1) Development of science and technology with molecular level

2) Resonance of science and technology

3) Evolution of interdisciplinary fields in the science and technology

4) Progress of super-technology

5) Development of modern science and technology associated with life and bio-organisms.

In the 20th century, medicine was extremely modernized by the introduction and application of the surrounding sciences and technologies. From the view points of medical technology, bio-medical engineering and bio-technology have played the great role to promote the progress of medicine.

In the 21st century, many sophisticated problems will remain to be solved with international level as follows:

1) Effective allocation of medical resources

2) Global solution on intractable diseases and huge accidents

3) Evolution of medical technologies and bioethics

4) Dialogue in "medicine and religion"

C-1

COMPARISON OF MOTOR CORTEX INDUCED-FLEXOR MUSCLE ACTIVITY INHIBITION BY HARD PRESSURE ON VARIOUS PARTS OF THE BODY AND LIGHT PINCH OF ABDOMEN OF ANIMAL WITH GASTRO-DUODENAL ULCERS

Tadashi Hisamitsu, M.D. Professor and Chairman.Department of physiology,School of Medicine, Showa University,Hatanodai, Shinagawa-ku, Tokyo, Japan.

ABSTRACT

The flexor muscle electromyogram (EMG) of the upper extremities in response to the motor cortex stimulation was inhibited by hard pressure on bases of ear lobe and lumber perivertebral region and by electrical stimulation of these regions. Similar inhibition was produced by electrical stimulation around the brachium conjunctivum and locus coeruleus (BC-LC) and the reticulogigantocellular nucleus (NRGC). Inhibition of the flexor muscle EMG due to hard pressure on the body parts was abolished by electrical lesion of the BC-LC and NRGC. The light pinch with hand on the restricted abdominal region did not inhibit the flexor muscle EMG induced by the motor cortex stimulation in normal condition, while such stimulation inhibited the flexor muscle EMG in ulcer suffering animals after treatment with cysteamine. This inhibition was not influenced by destruction of the NRGC. From these results, it was concluded that inhibition of the motor cortex induced-flexor muscle activities caused by light pinch stimulation of the restricted abdominal region, as the model of the voluntary finger flexion inhibition in O-Ring test, was produced by spinal reflex inhibition.

C-2

MUSCLE FORCE MEASUREMENT FOR THE BI-DIGITAL O-RING TEST USING A COMPUTERIZED ELECTRO-MECHANICAL SYSTEM

Yasuhiro Shimotsuura, M.D., F.I.C.A.E.

Dept. of Medicine, School of Medicine, Kurume University Kurume, Director of Dept. of Medicine, St. Maria Hospital, Kurume; Assistant Prof. of Pathologic Nutrition, Shin Ei College, Kurume, Japan; Editor in Chief, Resonance, the official journal of the Japan Bi-Digital O-Ring Test Association

Takesuke Muteki, M.D., Ph.D., F.I.C.A.E ;Professor & Chairman, Dept. of Anesthesiology,

Kyuichi Tanikawa, M.D., Ph.D.;Professor & Chairman, Dept. of Medicine Kurume University School of Medicine

67 Asahi-machi, Kurume City, Fukuoka, Japan

ABSTRACT

Measurement of muscle force change during the Bi-Digital O-Ring Test (originally developed by Y. Omura, of New York) was critically evaluated using a computerized electro-mechanical system. This Bi-Digital O-Ring Test muscle force measuring device can automatically and graphically display pulling force, distance and time (horizontal axis), before during & after pulling the Bi-Digital O-Ring Test by a motorized pulling force control system, through its auto-analyzer, by replacing the examiner's human hand with an electro-mechanical puller with constant speed, which can be changed to different values.

In normal persons without any problems in the neck, arms, hands, and fingers, muscle force of the Bi-Digital O-Ring formed between the thumb and one other finger of the same hand showed the following order of magnitude: 1st-2nd fingers, 1st-3rd fingers, 1st-4th fingers, 1st-5th fingers. When pulling speed was too slow, particularly less than3cm/sec, muscle force change appeared as 2 or 3 peaks, and therefore it was impossible to obtain a reliable Bi-Digital O-Ring Test. When pulling speed was over 5 cm/sec, response was an ideal one peak type muscle force change in reference to time on the horizontal axis. Therefore, in order to do a reliable Bi-Digital O-Ring Test, it is important not to pull the Bi-Digital O-Ring too slowly, and one should pull with relatively fast speed of over 5 cm/sec.

This device was used to measure change of muscle force during the Bi-Digital O-Ring Test, where pulling by a human examiner's fingers was replaced by an electro-mechanical pulling system with constant speed of over 5 cm/sec. In the following commonly encountered different cases, the studies were carried out using this device.

1) Detecting pathological areas of the body in chronic gastritis and chronic pancreatitis.

2) Evaluating thymus function in normal healthy individuals, in which (as the only exception), results of the Bi-Digital O-Ring Test should be negative.

3) Effect of drugs.

4) Effect of cigarettes.

5) Detecting chlamydia positive & negative patients using chlamydia antibody as reference control substance.

In all of the above cases, statistically significant changes were obtained, and these findings supported the validity of the result of properly performed Bi-Digital O-Ring Test where pulling was done by the examiner's human hands. Using this O-Ring Test computerized device, we will be able to objectively study various aspects of phenomena associated with the Bi-Digital O-Ring Test.

C-3

CEREBROPHYSIOLOGICAL RESPONSE MECHANISM IN BI-DIGITAL O-RING TEST BY FREQUENCY ANALYSIS OF HUMAN BRAIN WAVES - EFFECT OF CHEMICAL SUBSTANCES -

Noriyuki Tani D.D.S., Shigeyuki Tanaka, Masaru Ono and Yoshihiro Yagyu First Department of Prosthodontics Meikai University School of Dentistry 1-1, Keyakidai, Sakado-shi, Saitama Prefecture

ABSTRACT

The Bi-Digital O-Ring test (O-ring test) developed in 1978 by Y. Omura as a new diagnostic approach has gained a wide-spread recognition in many countries of the world as a clinically useful test. In spite of and contrary to the simplicity of its procedure, its mechanism has remained largely unknown. It is especially obscure what cerebro-physiological changes are induced or how sensitive the cerebral recognition level is. In other words, since a stimulant applied in the O-ring test or given by a chemical substance produces very feeble stimulation, it still remains unknown whether the reaction occurring in the O-ring test is identical to the conventionally-defined cerebral evoked response or whether the reaction is induced through a completely different response mechanism. To determine the mechanism on a cerebro-physiologial level, it is necessary to define the potentiality of this test as a human cerebral sensor as so described in 1965 by Tsunoda and in 1986 by Kikuchi et al. Our presentation at the Third International Symposium on Acupuncture and Elerctro-Therapeutics has confirmed the potentiality of the O-ring test as a human cerebral sensor, because the reaction could be recognized as a cerebral response to weak light of 80 luxs. This study was undertaken to further confirm our previous results. Experiment was carried out using the same experimental system as in our previous study presented at the symposium to confirm the existence of cerebral responses to non-contact stimulation with chemical substances delivered at a distance of 1 or 15cm from the stimulation points at the regions of the oral cavity and stomach in 10 subjects. The chemical substances used as stimuli consisted of potassium cyanide, arsenic, paraformaldehyde, methyl methacrylate monomer, vitamin C and toothpaste. The following results were obtained:

1. When stimulated by a conventional manner of stimulation, cerebral evoked potential tended to appear acutely at stimulation. In the O-ring test with chemical substances, the appearance of the response (integration of 10-second values )tended to be suppressed.

2. The cerebral responses produced by stimulation of the oral cavity and stomach in a resting state with closed eyes were not symmetrical over both sides. Especially at the , , and 1 regions, the responses were dominant on the right temporal and left occipital areas. This finding does not agree with the earlier described symmetry of the cerebral response.

3. The characteristic finding in this experiment was the left-hemispheric dominance at the 2 region unlike the right-hemispheric dominance at other regions.

4. A distinct difference was found between the responses by stimulation with harmful substances and those by stimulation with harmless substances. However, there were no substance-related differences between the group of harmful substances and that of harmless substances.

5. Distance-related differences were demonstrated in the intensity of cerebral responses. Stimulation at a distance of 1cm frontally to the oral cavity induced strong cerebral responses to methyl methacrylate monomer, vitamin C and toothpaste.

6. In stimulation with potassium cyanide, arsenic and paraformaldehyde, the difference in distance produced no differences in the intensity of responses. It is considered that since the both substance groups induced cerebral responses at either distance as described in 4, potassium cyanide, arsenic and paraformaldehyde induced cerebral responses to almost the same degree at either distance, which accounts for the lack of significant differences.

Key words: human brain wave, Bi-Digital O-Ring Test, Cerebrophysiological responses, substances

D-1

MICROBIAL OR VIRAL INFECTION AT CARDIOVASCULAR REPRESENTAION AREA OF MEDULLA OBLONGATA AS SOME OF THE POSSIBLE CAUSES OF HYPERTENSION OR HYPOTENSION

Yoshiaki Omura, M.D., Sc.D., F.A.C.A., F.I.C.A.E.

Director of Medical Research, Heart Disease Research Foundation, New York, USA Adjunct Prof. of Pharmacology, Chicago Medical School, Chicago, USA Visiting Research Prof., Dept. of Electrical Engineering, Manhattan College, New York, USA Adjunct Prof., Dept. of physiology, School of Medicine, Showa University, Tokyo, Japan President, International College of Acupuncture and Electro-Therapeutics, New York, USA [Correspondence: 800 Riverside Drive (8-1), New York 10032 USA]

ABSTRACT

184 consecutive patients visiting our clinic were examined for adenocarcinoma of the stomach using the Bi-Digital O-Ring Test, with a microscope slide of adenocarcinoma of the stomach used as a reference control substance, 48(26%)of these patients showed an adenocarcinoma positive response by indirect Bi-Digital O-Ring Test, using a nurse trained in the technique as a 3rd person. All of these 48 individuals were evaluated by standard laboratory tests using x-rays following barium swallowing and gastroscopy, followed by biophysics. 4 of these 48 patients (8.3%) were confirmed to have cancer by standard laboratory tests. Among the patients who had negative Bi-Digital O-Ring Test response to cancer, not a single cancer was directed.

Subsequently, another 196 patients visiting the clinic with a variety of medical problems were randomly examined, and the same 196 patient were examined for adenocarcinoma of the stomach once a week for 3 weeks. Only those who consistently indicated adenocarcinoma of the stomach by the Bi-Digital O-Ring Test were given laboratory tests. 21 patients (11%) were adenocarcinoma positive all 3 times to the Bi-Digital O-Ring Test. All of these 21 patients were adenocarcinoma positive all 3 times to the Bi-Digital O-Ring Test. All of these 21 patients were examined by standard laboratory tests, and 5(23.8%) of these 21 were found to have adenocarcinoma of the stomach by standard laboratory tests, consisting of stomach x-rays after barium swallowing and gastroscopy followed by biopsy. This study indicates that the Bi-Digital O-Ring Test cancer screening is simple, safe and highly efficient in its cancer detection and is quick, safe and economical. We believe that it will play an important role in future early detection of cancer in the stomach as well as other types of cancer.

D-2

MEASUREMENT OF "FLOW" AND THE BI-DIGITAL O-RING TEST

Takesuke Muteki, M.D., Ph.D. Prof. & Chairman, Dept. of Anesthesiology & Director of Emergency Intensive Care Unit, Kurume University School ofMedicine, Kurume, Japan

Yasuhiro Shimotsuura, M.D., F.I.C.A.E. Dept. of Medicine, School of Medicine, Kurume University,Kurume City, Japan; Director, Dept. of Medicine, St. Maria Hospital Kurume City, Japan

ABSTRACT

In order to study the interrelationship between hemodynamic changes and Bi-Digital O- Ring Test findings of the tissue, the author simultaneously studied Bi-Digital O-Ring Test response and amount of tissue-blood (IHb) as well as hemoglobin-oxygen saturation index (ISo2) of the tip of the finger by arm lifting. By arm lifting, Bi-Digital O-Ring Test response became negative, while IHb became markedly diminished and ISo2 also diminished. After lowering the hand, Bi-Digital O-Ring Test response quickly changed to plus response, indicating normal. IHb also increased, but ISo2 increased only after time delay. When the changes in arm lifting were examined in diabetes mellitus patients, patients with cold or numbness in hands, or patients with clinical symptoms of autonomic nervous system abnormality, response time in the Bi-Digital O-Ring Test took much longer than in the normal group.

With vertical distance of over 20 cm from the tip of the finger to the aortic valve level of the heart, the Bi-Digital O-Ring Test becomes negative, in normal persons. However, in these above-mentioned pathological groups, the Bi-Digital O-Ring Test becomes negative with less vertical distance, Response to the Bi-Digital O-Ring Test has better correlation with ISo2 than with IHb.

The Bi-Digital O-Ring Test is useful in detecting abnormalities in tissue micro- circulation, particularly in patients with peripheral circulatory insufficiency with autonomic nervous abnormalities.

D-3

BASIC RESEARCH ON PULSE DIAGNOSIS USING A NEW REVOLUTIONAL MACHINE

Mitsuru Takashima Sony Corp., Research Institute of Wisdom

ABSTRACT

Referring the ancient Chinese medical practice of diagnosis-by using the various pressure of three fingers on the radial artery-, a new pulse diagnostic machine has been developed in Sony Corp,. It has been investigated that the modern medical informations can be taken from the radial artery by using three pressure sensors instead of three fingers. In order to achieve our study, the following requirements were given to the machine.

1) The sensor pressure is given and equalized by using a cuff and plastic plate.

2) 3 sensors have the special sensitivity for only alternative current (AC). (fc=1.5Hz 6dB /oct)

3) The pressure control of the cuff is regulated by the releasing high pressure air. (from homeostasis until 0 pressure in 60 seconds)

Furthermore, the sensors to measure the time information exactly with special attachments were developed which facilitated easy placement on the artery. In the traditional oriental pulse feeling diagnosis, the two popular varying pressures, high and low, were measured. The several modern medical informations could be obtained between those two pressures.

TjHigh pressure equals to the systolic pressure

1.charcteristics of the blood ejection

2.Blood plasma viscosity

3.Vasoactivity of total artery

UjLow pressure equals to the diastolic pressure

1.Peripheral resistance information

2.Vasoactivity of the radial artery

VjBetween systolic and diastolic pressure

1.Elasticity of the arterial wall

2.Blood flow speed under the diastolic pressure of the radial artery

In these informations, we can find out some rapid changing values which some stimulations to the mention carry on. We suppose that they are one part of Qi- circulation of pulse diagnosis which may show the psychological phenomena. Several thousand years ago, the pulse feeling diagnosis was existed and still remains in practice on over the world. The effectiveness by some modern simple methods was attempted to be proved and the marvelous observations by ancestors toward the human being were confirmed. Some modern informations from pulse diagnosis could be obtained. This study will create "The New Third Medicine" over oriental and western medicine. A New Pulse-diagnostic machine (Modern Pulse Diagnosis by 3 sensors) SONY Pulse Laboratory Mitsuru Takashima

Key word: Oriental method, Pulse diagnosis, Radial artery, 3 pressure sensors, Rheological effect.

E-1

Diagnosis and Treatment of the Allergy Type I Reaction Using the "Bi-Digital O-Ring Testh

Shigeaki Yamamoto,M.D. Director, Bi-Digital O-Ring Test Clinic, Chikamori Hospital, Kochi, Japan

Abstract

A useful method for the diagnosis and treatment of the allergy type I reaction was examined using the "Bi-Digital O-Ring Test". Among allergic diseases, bronchial asthma, allergic rhinitis, allergic conjunctivitis, atopic dermatitis, and most of the urticarias belong to the allergic type I reaction. The type I reaction is initiated by an antigen reacting with IgE antibodies on a mast cell, leading to the release of chemical mediators, which stimulate the organ to cause the symptoms. The existence of IgE, which is peculiar to the allergy type I reaction, was examined with the "Bi-Digital O- Ring Test" Holding IgE ,as the control reference substance, resonance phenomena were observed in organs with symptoms. For instance, a stimulus to the tracheobronchial representation point of a patient with bronchialasthma, a stimulus to the back of nose of a patient with allergic rhinities, a stimulus to the bulbar conjunctiva of a patient with allergic conjunctivitis, and a stimulus to the exanthema of a patient with atopic dermatitis or urticaria all reacted with a negative response in the "O-Ring". Resonance phenomena were also observed in vertebrae and costae, conspicuously at the spinous process of the seventh cervical vertebra of patients with the allergy type I reaction, and their degree was proportional to the allergic levels. The spinous process of the seventh cervical vertebra turned to a plus response with an effective anti-allergic agent, and turned to a minus response when the patient held the allergen in his hand. Also after an appropriate biostimulation (with acupuncture, moxibustion or low energy level laser irradiation etc.),not only this point but also the allergic organs turned to a plus response. The investigation of this phenomenon was done by stimulating two points with a short time-lag in between the stimulations. "Dominant Points" were discovered in the spinous processes of the fifth, sixth and seventh cervical vertebrae and in the spinous process of the first thoracic vertebra. Particularly the spinous process of the seventh cervical vertebra covered the largest area. In conclusion, the spinous process of the seventh cervical vertebra was found to be the representation point of the allergy type I reaction. Applying these phenomena and methods, accurate diagnosis and treatment of the allergy type I reaction was possible.

F-1

DETECTION OF ULTRAWEAK BIOPHOTON EMISSION FROM HUMAN BODY

Masashi Usa, Ph.D. Biophotonics Information Laboratories, Kaminoyama, Yamagata, Japan

Humio Inaba Tohoku Institute of Technology, Sendai, Japan

ABSTRACT

All living organisms are known to emit an extremely weak light often referred to as "Biophoton emission", that differs from the visible luminescence of firefly for example. Of a variety of biological specimens such as the tissue, cell or organelle under investigation, we have especially attempted to clarify the emission characteristics of ultraweak biophoton detected at the surface of human body. Here we introduce the new findings on certain physical and pathophysiological properties of human biophoton emission, including the data obtained in therapeutic "Qi-gong" experiments, as well as the basic principles of highly sensitive measurement techniques we developed.

f|P

COMMON FACTORS CONTRIBUTING TO INTRACTABLE PAIN AND MEDICAL PROBLEMS WITH INSUFFICIENT DRUG UPTAKE IN AREAS TO BE TREATED, AND THEIR PATHOGENESIS AND TREATMENT: PART I. @CONBINED USE OF MEDICATION WITH ACUPUNCTURE, (+)QI GONG ENERGY-STORED MATERIAL, SOFT LASER OR ELECTRICAL STIMULATION

Yoshiaki Omura, M.D.,Sc.D.,F.A.C.A.,F.I.C.A.E. Director of Medical Research, Heart Disease Research Foundation, New York, USA Adjunct Prof. of Pharmacology, Chicago Medical School, Chicago, USA Visiting Research Prof., Dept. of Electrical Engineering. Manhattan College New York, USA Adjunct Prof., Dept. of Physiology, School of Medicine, Showa University, Tokyo, Japan President, International College of Acupuncture and Electro-Therapeutics, New York, USA [Address: 800 Riverside Drive(8-I), New York, NY 10032 USA]

Bro. Michael Losco, M.Sc., F.I.C.A.E., Assistant Prof. Dept. of Electrical Engineering, Manhattan College, New York & Member, Board of Trustees, Heart Disease Research Foundation, New York, USA;

Alexander K.Omura,MD.,Dept.of Surgery, Mayo Graduate School of Medicine, Rochester, Minnesota, USA;

Chifuyu Takeshige, M.D., Ph.D., F.I.C.A.E., Prof. Emeritus and Former Chairman of Dept. of Physiology, and Former Dean, School of Medicine, Showa University, Tokyo, Japan and the members of his former departmental staff; Tadashi Hisamitsu, M.D., Ph.D., F.I.C.A.E., Prof. & Chairman, Dept. of Physiology, School of Medicine, Showa University, Tokyo, Japan; Yasuhiro Shimotsuura, M.D., F.I.C.A.E.,Director of Medicine, St. Maria Hospital, Kurume,Japan; Executive Secretary, Japan Bi-Digital O-Ring Test Assn; Shigeki Ymamoto, M.D., Director, Bi-Digital O-Ring Test Clinic, Chikamori Hospital,Kouchi, Japan; Hyoe Ishikawa, M.D., Ph.D., F.A.C.C., Prof, and Chairman of Dept. of Internal Medicine, and President of Nara Medical College, Nara, Japan, and the members of his departmental staff; Hiroaki Nakajima, M.D., Ph.D., Associate Prof., Dept. of Internal Medicine, School of Medicine, Showa University, Tokyo, Japan. Claire Urich, B.S., Research Assistant, Heart Disease Research Foundation, New York, U.S.A.

ABSTRACT

Most frequently encountered causes of intractable pain and intractable medical problems, including headache, post-herpetic neuralgia, tinnitus with hearing difficulty, brachial essential hypertension, cephalic hypertension and hypotension, arrhythmia, stroke, osteo-arthritis, Minamata disease, Alzheimer's disease and neuromuscular problems, such as Amyotrophic Lateral Sclerosis, and cancer are often found to be due to co-existence of 1) viral or bacterial infection, 2) localized microcirculatory disturbances, 3) localized deposits of heavy metals, such as lead or mercury, in affected areas of the body, 4) with or without additional harmful environmental electromagnetic or electric fields from household electrical devices in close vicinity, which create microcirculatory disturbances and reduced acetylcholine.

The main reason why medications known to be effective prove ineffective with intractable medical problems, the authors found, is that even effective medications often cannot reach these affected areas in sufficient therapeutic doses, even though the medications can reach the normal parts of the body and result in side effects when doses are excessive. These conditions are often difficult to treat or may be considered incurable in both Western and Oriental medicine. As solutions to these problems, the authors found some of the following methods can improve circulation and selectively enhance drug uptake:

1) Acupuncture, 2) Low pulse repetition rate electrical stimulation (1-2 pulses/second), 3) (+) Qi Gong energy, 4) Soft lasers using Ga-As diode laser or He-Ne gas laser, 5) Certain electromagnetic fields or rapidly changing or moving electric or magnetic fields, 6) Hear or moxibustion, 7) Individually selected Calcium Channel Blockers, 8) Individually selected Oriental herb medicines known to reduce or eliminate circulatory disturbances.

Each method has advantages and limitations, and therefore the individually optimal method has to be selected. Applications of (+) Qi Gong energy stored paper or cloth every 4 hours, along with effective medications, were often found to be effective, as Qigongnized materials can often be used repeatedly, as long as they are not exposed to rapidly changing electric, magnetic or electromagnetic fields. Application of (+) Qi Gong energy-stored paper or cloth, soft laser or changing electric field for 30-60 seconds on the area above the medulla oblongata, vertebral arteries or endocrine representation area at the tail of pancreas reduced or eliminated microcirculatory disturbances and enhanced drug uptake. In order to apply only (+) Qi Gong energy and prevent any potential adverse effects of applying (-) Qi Gong, which often induces vaso-constriction, a simple test to evaluate which parts of the right and left hands, right and left feet, and face emit (+) or (-) Qi Gong, is shown for the first time.

In right-handed individuals, each fingertip of the right hand emits (+) Qi Gong energy. From the right palm, several round spots emit (-) Qi Gong energy, including 2 distinctive coin-shaped areas (one of them being Pc.8). In the left hand, each fingertip emits (-) Qi Gong energy. In the palm of the left hand, each fingertip emits (-) Qi Gong energy. In the palm of the left hand, several round spots corresponding to the right hand emit (+)Qi Gong energy. The soles of the feet emit the same patterns as the corresponding hands. On the face, the right eye and the areas between the eyebrows (known as "Yin Tang") emit(-) Qi Gong energy. The left eye and the nose and lips emit (+) Qi Gong energy. Using the Bi-Digital O-Ring Test, determination and localization of pathogenesis and applications of some methods of effective treatment, including inducing enhancing drug uptake of effective medication into diseased areas which are considered to be difficult or impossible to treat, will be presented, with examples of successful treatments.

G-2

CORRELATION OF THE PINEAL BODY WITH EEG CHANGE AFTER QI AND MAGNETIC FIELD

Chifuyu Takeshige, M.D., Sc.D., F.I.C.A.E. Emeritus Professor of Showa University 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142

ABSTRACT

We previously found that milligauss order of magnetic field radiated from the acupuncture point such as Laokung in special Qi trained person during internal Qi emission. Semm et al. shown that the pineal gland cells responded to the earth magnetic field. We reconfirmed this fact in rat. i.e. spontaneous electrical activity of the pineal cells was depressed by changing horizontal direction of the head from south to north. Furthermore it was extremely depressed by putting Qi medal 2 cm above head. Qi medal should have Qi which was given by a Chinese Qi trained person, Tong Zheng. It was reported that the special pattern of EEG appeared during emission of the internal Qi or applying the external Qi. Possibility that mediation of the pineal gland in such EEG change during Qui emission was examined by comparison between EEG changes during application of Qui medal and those after pineal ectomy in rabbits. EEG recorded from different parts with 6 electrodes buried in the cranial bone was analyzed by Neuromap (Nihonkoden Co.,Tokyo) which denotes the topographical magnitude of EEG by color expression.

Analyzed frequency bands of EEG for rabbits were 1.50-3.49, 3.50-5.99, 6.00-8.99,9.00-10.99, 11.00-12.99 and 13.00-16.99 Hz. Integrated EEG for 2 sec was averaged 60 times for 2 min which gave the stable control. When Qi medal was put 2 cm above cranial bone for 2 min, 3.50-5.99 Hz band enhanced alone and all other bands were depressed. This EEG change was further confirmed by Z-map which gave deviation ( }3 ) from control value by color expression. Such EEG change was always obtained at least initial 2 min after Qi application not correlated with animal (n = 4) and application time in a day and in different day (8/8).

Quite similar EEG change was obtained by application of the static magnetic field of 150 Gauss which is intensity 3 cm apart from magnetic source and is equivalent strength to the pineal gland since the pineal gland is located 1.0 cm depth below cranial bone surface and magnetism was applied 2 cm above cranial bone. Threshold strength of magnetic field to cause EEG change might be 25 Gauss since 1 of 4 examined animals did not respond to this intensity. After pineal ectomy, EEG changes due to Qi medial and magnetic field disappeared i.e. EEG was not changed by both. Since many investigators reported that magnetic field inhibits N-acetylserotonin transferase (NAT) which degrades pineal serotonin to N-acetylserotonin and as a result, contents of pineal serotonin increased and that of melatonin decreased. Appropriate doses (5 mg/kg, i.v.) of serotonin precursor, 5 hydroxytryptophan (5HTP) changed EEG similar to that after application of Qi medal or static magnetic field. After pineal ectomy, such EGG change disappeared. Under this condition, about two times doses of 5HTP were necessary to produce EEG change similar to that after Qi or 5 mg/kg 5HTP.

A general serotonin antagonist, methysergide (3-6 mg/kg, i.v.) did not antagonized EEG change due to Qi medal and 5HTP (5 mg/kg, i.v.)

In conclusion, EEG change after magnetic field might be mediated by increased serotonin in the pineal gland due to inhibition of NAT enzyme and it was strongly suggested that Qi medal acts on the pineal body and inhibits NAT activity, and increase of pineal serotonin changes EEG.

G-3

Recognition of Qi Gong " How far can Science define Qi Gong? "

Yutaka Haruki, Ph.D. Prof. Dept. of Human Science, Waseda University, Tokyo, Japan

ABSTRACT

Various things have been said about Qi Gong by various people who have their background in the field like physics, physiology, psychology, medicine, or even thoughts or religion. That explains why we have not been able to understand what Qi Gong really is. Therefore, what we must do right now is to study the paradigm that defines the way to understand Qi Gong.

The first premise to understand the essence of Qi Gong is the fact that, unlike a natural phenomenon, a human being always takes part in Qi Gong. The second premise is the fact that human mind takes part in it. The third premise is that we understand Qi Gong only by experience, not by thoughts or logic. Taking these premises into account, the paradigm defining Qi Gong is considered to be the one below.

INPUTS HUMAN BEING OUTPUTS

Information Report

Image Direct Action

Action Experience Physiologic Stimulus Reaction (Sight, etc.) Physical Medicines Reaction

Indirect Experience

(Science)

Although we could learn Qi Gong by experience, we have to know there are two kinds of experience. One is direct experience, and the other is indirect experience. For example, it is a direct experience that we perceive the moon on the horizon small, and that the moon on the meridian big. On the other hand, it is an indirect experience that we find two different things are of the same length (that we find two different things in photographs are of the same size) since the experience can be had by the medium of a scale (a camera). Direct experience itself cannot be had jointly with others. Even so, it is the experience that cannot be denied for that particular person. It is indirect experience that can be had jointly with others, and that is scientific recognition. Therefore, we should know there are two ways to learn Qi Gong: by direct experience, and by indirect experience (science, that is). As the diagram above indicates, the scientific recognition of Qi Gong is the confirmation of the facts (the conditions of the inputs, as well as the phenomena of the outputs which occur to human being and also are caused by such inputs) and the inference of the relationships between those inputs and outputs. The experience of Qi Gong itself is direct experience, so it cannot be had jointly with others. The direct experience of Qi Gong is only personal. The important thing we all should remember is that both direct experience and indirect experience are equally valuable.

H-1

Whither the Pain Pathway?

Albert W.Cook,M.D.,F.I.C.A.E. Director, Dept. of Neuroscience, Long Island College Hospital, New York, USA; Prof. & Former Chairman, Dept. of Neurosurgery, Downstate Medical Center, New York, USA

ABSTRACT

Pain is experienced because of transmission of signals through the nervous system from distal sites which have been injured. It is a warning system. It has been promulgated that there exist specific so-called pain pathways for transmission of these signals. I will demonstrate that pain in not permanently abolished by destroying surgically these very seemingly specific pathways. In this work, evidence will be presented that great portions of the spinal cord in man can be destroyed and pain still will be experienced. The experience of pain in man primarily is so essential that its existence is exquisitely protected. In fact, it is virtually almost impossible to abolish permanently by surgical means the experience of pain. The question then can rightly be asked, "Where is the pain pathway?" I will attempt to answer the question. In studying & mapping the pain pathway non-invasively in living human the Bi-Digital O-Ring Test became a very powerful tool.

H-2

THE ENKEPHALINASE MECHANISMS OF MORPHINE TOLERANCE

Kalyuzhnyi L., M.D., Sc.D., Kozlov A., Litvinova S.* Institute of Normal Physiology of Russian Academy of Medical Sciences *Department of Higher Nervous Activity of Moscow University

ABSTRACT

It's known that the chronic morphine administration, using at the post-operation time and for chronic pain syndrome treatment, induced the tolerance i.e. a loss of the analgesic effect of a fixed dose of morphine, that requires to increase one for analgesia but large doses produce severe side effects in some patients. However, the mechanisms of morphine tolerance are not clear up today. It was suggested that this mechanism is determined by the alteration of the opiate receptor numbers, of the binding, of the affinity to the opioids or to it's antagonist. But the subsequent researches didn't confirm these suggestions (Pert C. et al., 1973; Davis M et al., 1975;Perry D. et al, 1982; Zwartau E., 1984). At the last time the low level of endogenous opioids in morphine-tolerant and morphine-insensitive animals has been established (Takeshige C. et al., 1979; Gudehithlu K. et al., 1991). These results confirm the hypothesis of the inhibition of opioid release in morphine-insensitive and morphine-tolerant animals suggested by Kosterlitz H.A. Huges J. (1975). However it's known that the mechanism of uptake for endogenous opioids haven't been established and the low level of opioids could be induced by its degradation due to peptidase activity (Shaw S. et al., 1978, Zajac J. et al., 1990). In the last years our researches showed that about 70% of Wistar rats were sensitive to morphine (1.5 mg/kg) analgesic effect estimated by the increasing of tail-flick latency, but about 30% were insensitive. In morphine-sensitive rats the isolated enkephalinase inhibitor-d-Phenylalanin (d-Pha) application (i.p. 300-600 mg/kg) didn't change the nociception but in morphine-insensitive rats induced dose depended analgesic effect, just after the cessation of which, morphine injection induced analgesia. In morphine-sensitive rats naloxone (0.3 mg/kg) application induced either hyperalgesia or the absence of nociceptive alteration and blocked morphine analgesia. In morphine-insensitive rats naloxone (0.2-0.7 mg/kg) induced analgesic effect, just after cessation of which morphine application induced analgesia, but naloxone (1.0 mg/kg) induced hyperalgesia. In morphine-sensitive rats chronic morphine administration induced the gradual decrease of its analgetic effect which disappeared for a 2-5 injections in full, i.e. morphine-sensitive rats became morphine-tolerant ones. In these morphine-tolerant rats the isolated d-Pha or naloxone application induced analgesic effect just after the cessation of which morphine injection induced analgesia. However, next day after d-Pha or naloxone application morphine injection didn't induce the analgesic effect. As our experiments showed in morphine-insensitive and morphine-tolerant rats the chronic naloxone administration induced the gradual decrease of its analgesic effect which disappeared for 2-7 injection in full that resulted to the manifestation of subsequent morphine analgesic effects for some applications. Thus morphine-insensitive and -tolerant rats became morphine-sensitive again. Thus one can think that in the morphine-insensitive and morphine-tolerant rats there is a high level of enkephalinase activity which has been established also by biochemical researches (Malfroy B. et al., 1978). This high level seems to be absent in morphine-sensitive rats because d-Pha didn't change the nociception in these animals. But d-Pha induced analgesia in morphine-insensitive and -tolerant rats that seems to decrease the ehkephalinase activity that lead to the opioid release and morphine analgesic effect manifestation. Thus one can suggest that in morphine-insensitive rats there is a genetic but in morphine-tolerant animals there is an acquisitive high level of enkephalinase activity which evokes the high speed of endogenous opioid degradation and by this way blocks the morphine analgesic effect which is realized by the endogenous opionoid release (Kachur J. et al., 1985). Naloxone in used doses and in the conditions of high enkephalinase activity seems to have an enkephalinase inhibitor properties, which is manifested in the lowest doses in morphine-sensitive beings (Ueda H. et al.,1986).

H-3

CURRENT THERAPY FOR THE TREATMENT OF PAINFUL CONDITIONS

Saymour Ehrenpreis, Ph,D. Department of Pharmacology and Molecular Biology and Medicine, Chicago Medical School, North Chicago, IL USA 60064

ABSTRACT

Recent developments in the treatment of various painful conditions will be reviewed. The modalities of therapy to be considered will include the following:

1. Acupuncture

2. E TENS

3. Acupuncture or TENS plus an enkephalinase inhibitor (Diphenylalanine)

4. Enkephalinase inhibitors alone

5.Drugs: Opioids, NSAIDs, anti-depressants, anti-convulsants, phenothiazines, alone or in combination administered by different routes including spinal

6. Antiviral agents acyclovia, EPA with DHA etc.

The painful conditions to be considered are as follows:

1. Cancer

2. Back pain

3. Headaches of various types

4. Facial (trigeminal neuralgia)

5. Joints

The newer information about these different modalities of treatment should enable the physician to treat various painful conditions, especially the chronic ones, with a greater degree of success.

H-4

BI-DIGITAL O-RING TEST AS A DIAGNOSTIC AND PROGNOSTIC AID IN ACUTE NECK AND SHOULDER PAIN.

Pekka J. Pontinen, M.D., Ph.D., F.I.C.A.E., F.A.C.A., F.A.A.A. Assoc. Prof. of anesthesiology, Tampere University; Consultant, Dept. of Neurology, Tampere University Hospital; Lecturer,Institute of Extension Studies, Tampere University; Tapere, Finland. Assoc. Prof. of anesthesiology, Kuopio University; Director, Acupuncture Research Project, Institute of Physiology, Kuopio University, Kuopio, Finland. Former Medical Director, Kankaanpaa Rehabilitation Center, Kankaanpaa, Finland. Editor-in-Chief, Scandinavian Journal of Acupuncture & Electro-therapy; Editor, Acupuncture & Electro-Therapeutics Research, the International Journal; Editor,Aku, Akupunktur-Theorie Und Praxis.

Abstract

Neck and shoulder pain with related impairment in the function of the upper extremity are everyday problems in pain clinics and in sports medicine and rehabilitation. Acute, unbearable pain with or without neurological deficit signs in neck and upper extremity provides a challenge to every clinician. Is the origin of pain and dysfunction peripheral or central. Is it an acute activation of latent triggers in neck and shoulder muscles induced by overspending at work or overloading in sports? Or is there a discogenic lesion and compression of nerve root? In stead of expensive CT and MRI imaging we may apply simple and inexpensive methods to locate the site of pathology. We may use pressure algometry for quantitative assessment of tenderness and more accurate location of trigger point (1-4). Pressure threshold measurement (PTH) is useful for documentation of improvement after treatment (5). Simple hand dynamometer (Vigorimeter, Gehrnder Martin, Tutlingen,Germany) gives us valuable information of the functional state of the muscles. We should take both the maximal grasping force and a series of 10 measurements for detection of early fatigue which is typical in myofascial trigger activity and fibromyalgia. In discogenic lesions the maximal grasping force is low from the very beginning. The whole hand grasping force does not help us to localize the pathological segment. We should always compare the individual fingers against thumb, too. This can be done with the same dynamometer using a smaller ball between thumb and the finger to be measured. This is often difficult and the results are not entirely reliable. We may instead use Bi-Digital O-Ring Test for evaluation of individual finger force and thus locate abnormal cervical segments (6,7). A relative weakness in the index finger reflects dysfunction from organic pathology at C(3-4)5(6) level, correspondingly the 3rd finger at C(5)6(7) level, the 4th finger at C(6)7(8) and the 5th finger at C(7)8(Th1) level. There is always some overlapping and therefore some segments are in parenthesis. We may locate the local paraspinal points which correspond the pathological segment through their tenderness when palpated or better still, documented with pressure algometry. Another important localizing method is Bi-Digital O-Ring Test to locate exactly both paraspinal site of lesion and peripheral trigger and acupuncture points involved. To confirm the functional importance of the paraspinal point (site of the lesion) we may either insert a small size acupuncture needle intracutaneously exactly to this location or give it a low dose of laser irradiation (e.g. 0.1-0.2 J/point). The immediate restoration of muscle strength checked with hand dynamometer and Bi-Digital O-Ring Test confirms the segmental level in functional disorders. After a positive test dose we should continue with a normal laser dose (2 J/local paraspinal point, 1 J/trigger point). No change marks either improper location or permanent organic failure in myoneural function. These patients may need further neurological evaluation (e.g. thermography, CT, MRI). Recently we have found that in acute discogenic lesions verified by CT and/or MRI laser irradiation may restore normal myoneural function and may give complete pain relief in about 15 minutes from irradiation. The reasoning is, that laser increases micro-circulation and improves lymphatic flow which reduce local edema and inflammation caused by disk protrusion and relieves pressure on the nerve root involved. Pressure algometry, head dynamometry and Bi-Digital O-Ring Test should become normal after a successful treatment.

References:

1. Airaksinen, O, Pontinen, PJ: The reliability of the pain threshold algometry on latent myofascial trigger points in healthy Finnish students. 1st Intern'l Symposium on Myofascial Pain and Fibromyalgia, Minneapolis, Minn 8-10 May, 1989.

2. Fischer, AA: Application of pressure algometry in manual medicine. J Manual Medicine 1990, 5, 145-150.

3. Makela, S, Pontinen, PJ: Reliability of pressure threshold meter in location of latent trigger points in healthy subjects. Scand J Acup Electrother 1988, 3, 45-50.

4. Pontinen, PJ, Vuoto, L: Pressure algometry in low back pain patients and healthy controls. Myopain'92, 2nd World Congress on Myofascial Pain and Fibromyalgia, Copenhagen 17-20 August, 1992.

5. Airaksinen, O, Rantanen, P, Kolari, PJ, Pontinen, PJ: Effects of infrared laser irradiation at the trigger points in healthy subjects. Scand J Acup Electrother 1988, 3, 56-61.

6. Omura, Y: Practice of Bi-Digital O-Ring Test. Ido-No-Nippon-Sha, Tokyo and Yokosuka 1986 (1st ed), 1989 (6th ed).

7. Pontinen, PJ: Some new aspects in the treatment of hemicrania by acupuncture. Scand J Acup Electrother 1986, 1, 17-22.

Address for correspondence: Pikkusaarenkuja 4 B 77, SF-33410 Tampere, Finland, fax.358-31-462441

g|T

Usual and Unusual Diagnostic and Therapy of Chronic Pain In Germany

Use of Bi-Digital O-Ring Test

Thomas Floter M.D.,F.I.C.A.E. President, Schmerz-Therapeutisches Kolloquium,and Pain Treatment Center of Frankfurt, Germany

ABSTRACT

The care of chronic pain patients in Germany is still Incomplete. Out of approximately six million chronic pain 600 thousand require a special algesiologic treatment. 1500 pain centers are necessary for these patients, although there are only 150 in existence. The most significant reasons for the low level of care are lacking appreciation of the problem, lacking further education, confusion over acute and chronic pain, improper use of the information available, deficiencies in research, and restrictive legislation (Health System Structure Reform Law and Drug Law). The SCHMERZ Therapeutisches Kolloquium (Pain Forum),which has over 2000 members, has achieved pioneering work for 10 years: definition of the algesiologist and implementation of the necessary further education. The diagnostic and therapeutic spectrum of pain therapy is wide, there are common and uncommon methods of treatment. The usual clinical diagnosis is completed first of all with diagnostics using the five senses; the measurement of pain is too detailed for the everyday clinic. Algopressuremetrics and psychological methods of testing (visual analogue scales and psychometric tests) have proved useful. Still unusual, though firmly integrated into our work, is the diagnostic investigation with the Bi-Digital O-Ring Test. Since 1984 we held a dozen courses with Prof. Omura and Prof. Pontinen, and trained several hundred participants of these courses. We use this simple kind of test to measure and localize pain and for therapy control. The Bi-Digital O-Ring Test also proved highly useful in the testing of pharmaceuticals: selection of the medication, establishing of dose, and tolerance tests. We also test foodstuffs within the framework of establishing a pain relieving alimentation program. In connection with this special diet it proved useful to train the patients and their family in the handling of this test. The Bi-Digital O-Ring Test is highly reliable in the case of food intolerance and allergies to foodstuffs. The limits of such a sensitive test are soon reached if positive findings are misinterpreted, e.d, it would be fatal to infer a clinically manifest carcinoma disease from the finding of individual carcinoma cells. The Bi-Digital O-Ring test in non-invasive, harmless and also lower priced than many other diagnostic methods. In our experience with many hundred patients the Bi-Digital O-Ring Test means a useful complement to the diagnostic methods of traditional medicine if it is used properly and with an eye to reality. Electric test devices, though being more impressive for patients, seem to be inferior to the Bi-Digital O-Ring test as concerns accuracy and reproducibility of the results. We only want to briefly enumerate the therapeutic methods used and approved of in Germany: pharmacotherapy, neural blockade, physical therapy, mutual therapy, acupuncture, transcutaneous electric nerve stimulation, laser, psychotherapy, peridural application of opiates, pain surgery, neurolytical nerve blocks. Unusual, though proven, tried and tested in practice, are the following methods,e.d.: cupping, cantharidin plaster, Baunscheidt's airpuncture treatment subcutaneous CO2-insufflation, spiritual healing, homeopathy, anthroposophy, reflexotherapy, physiotherapy, chiropodology, pain-relieving nutrition. We want to take a closer look at pharmacotherapy, because a new study is to be presented. In drug therapy we are have to combat ignorance, prejudice and restricting statutory regulations.

According to popular medical opinion the opiates should only be given to terminal cancer patients. The reality, however, is that there are many conditions of pain which can be controlled only with the opiates. In order to reduce ignorance and prejudices we performed a retrospective study investigating the effectiveness and compatibility of centrally acting analgesics in long-term therapy. Special regard was directed towards compliance, patient condition and adverse effects. Analyzed were the data of 412 patients, average age 64 years. The majority of the patients suffer from pain of non-malignant origin (e.g. arthroses, stump and phantom pain, and neuralgias). The average therapy lasted for half a year, compatibility was very good, regularly reported was only constipation due to morphine. None of the patients developed dependency or addiction. The doses established for the different opiates were tested with the Bi-Digital O-Ring Test. Chronic pain often needs to be treated continually for years with potent and most potent analgesics; complementary pain therapy procedures should supplement therapy.

g|U

MY PATH TO THE BI-DIGITAL O-RING TEST

Soren Jorgensen, M.D. Prof. & Former Chairman, Dept. of Anaesthesiology,Odense University, Odense, Denmark

ABSTRACT

A brief summary is given of a Danish aneasthesiologist's disappointing experience throughout many decades with the so-called blockade treatment using local anaesthetics in the treatment of chronic pain. This was followed by a gradual transition to the use of acupuncture after much hesitation in both hospital work and in private practice.bbAcupuncture carried out single handed in a hospital when surrounded, at least at the start, by colleagues shaking their heads, was very instructive, but did not permit of any research. However, increasing experience throughout a period of more than ten years of clinical work together with 3 to 4 years of study and continued clinical work, have shown that the results of treatment are of such a character that they are of great value to a vast majority of patients. Throughout the last 2 years, the Bi-Digital O-Ring Test, employing in the main, the indirect method, has been used for diagnostic purposes and as a standard procedure together with my general medical judgment for evaluating the results of treatment. Practical examples will be demonstrated with the help of slides. Almost all of our patients had been treated by their own physician, and frequently also by various specialists before being referred to our clinic. We are able to improve the lot of more than one half of our patients. Should we be unable to do so using these methods then we naturally employ the well-known analgesic drugs available to all physicians. If the condition is not improved then it may be the physician who is at fault, not the patient. The instruction of senior medical students will be mentioned. The Bi-Digital O-Ring Test is in my opinion a method of examination which is just as valid as testing tendon reflexes. However, Western Science (and the Japanese) will demand parameters which can be repeated and reproduced. The fact remains that those of us who are convinced of the method's efficacy must find more exact measures of the method in order to overcome the general skepticism. Questions will be asked as to the nature of the method and its reliability.

H-7

Simple Non-invasive Mapping of Pain Pathways in Living Humans, and Effects of Acute Non-invasively induced Pain on Substance P, Oncogen C-fos Ab1, Oncogen C-fos Ab2, Dopamine, and Acetylcholine

Yoshiaki Omura, M.D, Sc.D., F.A.C.A,F.I.C.A.E. Director of Medical Research, Heart Disease Research Foundation, New York, USA Adjunct Prof., Dept. of Pharmacology, Chicago Medical School, Chicago, USA Visiting Research Prof., Dept. of Electrical Engineering Manhattan College, New York, USA Adjunct Prof., Dept. of Pharmacology, School of Medicine, Showa University, Tokyo, Japan President, International College of Acupuncture and Electro-Therapeutics, New York, USA [Correspondence: 800 Riverside Drive (8-1), new York, NY 10032 USA]

Bro. MIchael Losco, M.Sc., F.I.C.A.E., Assistant Prof. Dept. of Electrical@Engineering, Manhattan College,

New York & Member, Board of Trustees, Heart Disease Research Foundation, New York, USA;

ABSTRACT

Most of the present knowledge on pain pathways is based on invasive animal experiments as well as human clinical cases. In 1987, using the Bi-Digital O-Ring Test, Omura found that pain pathways can be evaluated non-invasively in living humans. In this paper, actual examples of such cases a reported. When mild pain was created by pinching different fingers of a normal human subject by placing a plastic clamp on the skin above a pain pathway, the indirect Bi-Digital O-Ring Test, through a fine electro-conductive metal wire held by a third person, showed marked weakening of muscle tone of the third person resulting in the opening of the Bi-Digital O-Ring, which was reselected only when the minimum essential requirements to perform the Bi-Digital O-Ring Test were satisfied. The pain pathway thus detected had the following characteristics: For example, when the lateral side of the 5th finger of the left hand was pinched, the pathway was approximately along the ulnar nerve and then went to the dorsal root of the spinal cord around the area corresponding to the lower end of the 7th cervical vertebrae/upper end of the 1st thoracic vertebrae. At this level, the pain pathway goes to the opposite side (right side) then laterally up to the lower one-third of the medulla oblongata. It then turns horizontally from the right side to the left side at the same level, then goes up in the left side of the center of the medulla oblongata. At the left side it goes to the pons it turns towards the midline. It then goes up and turns to the right side of the right cerebral cortex corresponding to the lateral side of the 5th finger. A similar pattern was observed through the corresponding nerve for each of the fingers, and their entry points are as follows: the medial side of the 1st finger goes to the lower end of the 4th cervical vertebrae, and the lateral side of the 1st finger goes to the upper end of the 5th cervical vertebrae; the medial side of the 2nd finger goes to the lower end of the 5th cervical vertebrae, and the lateral side of the 2nd finger goes into the upper end of the 6th cervical vertebrae; the medial side of the 3rd finger goes in at the upper edge of the 6th cervical vertebrae, and the lateral side of the 3rd finger goes into the upper end of the 6th cervical vertebrae; the medial side of the 4th finger goes into the lower edge of the 6th cervical vertebrae, and the lateral side of the 4th finger goes into the upper edge of the 7th cervical vertebrae; the medial side of the 5th finger goes into the lower end of the 7th cervical vertebrae, and the lateral side of the 5th finger goes into the upper end of the 1st thoracic vertebrae. The patterns of the pain pathways made detectable by stimulation of other parts of the body are more or less similar and end up in the corresponding area of the sensory cortex of the opposite cerebral hemisphere of the brain. As soon as the clamp was applied along this pain pathway, Substance P, Oncogen C-fos Ab1, Oncogen C-fos Ab2 and Dopamine increased along with the disappearance of Acetylcholine. However, as soon as the painful clamp was removed, Substance P, Oncogen C-fos Ab1, Oncogen C-fos Ab2 and Dopamine disappeared, with the reappearance of Acetylcholine. This method can be used for the evaluation of normal pain pathways and other sensory nerve pathways and provide valuable information on short-lasting dynamic bio-chemical changes in a pain pathway which cannot be easily detected in living humans.

Key words: Pain, Pain pathway, Spinal cord, Medulla oblongata, Pons,

h|P

ENVIRONMENTAL ELECTOMAGNETIC FIELDS AS A POTENTIAL CONTRIBUTING@FACTOR IN VARIOUS MEDICAL PROBLEMS & UNIQUE CHARACTERISTICS OF ELECTROMAGNETIC FIELD-INDUCED PATHOLOGY IN HUMANS

Yoshiaki Omura, M.D, Sc.D., F.A.C.A,F.I.C.A.E. Director of Medical Research, Heart Disease Research Foundation, New York, USA Adjunct Prof., Dept. of Pharmacology, Chicago Medical School, Chicago, USA Visiting Research Prof., Dept. of Electrical Engineering Manhattan College, New York, USA Adjunct Prof., Dept. of Pharmacology, School of Medicine, Showa University, Tokyo, Japan President, International College of Acupuncture and Electro-Therapeutics, New York, USA [Correspondence: 800 Riverside Drive (8-1), new York, NY 10032 USA]

ABSTRACT

Using the Bi-Digital O-Ring Test, it is possible to localize potentially harmful electromagnetic fields corresponding to more than 10V/m for Extremely Low Frequency of 30-1000Hz and more than 1V/mfor Very Low Frequency of 2-400KHz. However, certain electromagnetic fields cannot be easily measured by commercially available standard instrumentation, while most harmful electromagnetic fields can be detected by the Bi-Digital O-Ring Test. Following is a summary of the unique characteristics found in electromagnetic field-induced pathological parts of the body. 1) Almost identical shaped electromagnetic field-induced imprints of abnormalities exist simultaneously at the back of the body (EMF entry area) and front of the body (EMF exit area), if the EMF is coming from under the bed (or from the wall) where the individual sleeps (or sits near) every day for prolonged periods of time. If there are symptoms, some of them will be worst when the individual wakes up in the morning. If the EMF frequency is extremely high, such as in the microwave range, at least after 7 or 8 hours exposure per day for more than 2 weeks, on the body surface, characteristic EMF-induced pathological imprints on the cross-sectional area of the body can be detected by the Bi-Digital O-Ring Test before any symptoms appear. Usually, it takes more than 1-3 years of daily EMF exposure of several hours symptoms or pathological changes appear. 2) Abnormal electromagnetic fields from under the bed (or from a nearby wall) often appear as a band-like shape in a cross-sectional plane through the front and back of the body. Such abnormality appears as if the person is wearing a sash, as the EMF passes straight through the human body from the entry area to exist area in a cross-sectional plane.

3) When 2 or more abnormal electromagnetic fields are coming from band-shaped areas and are crossing each other, at such a crossing area, the maximum abnormality appears as in the EMF exposed area of an individual sleeping for a prolonged period of time, due to summation of EMF at the crossing areas. Such an EMF crossing area often corresponds to the pathological locations of human cancers, stroke, acquired epilepsy, localized circulatory disturbances, or intractable chronic pain, etc.

4) The most common electromagnetic field induced imprint on the body appears as a cross- sectional belt-shaped (band-shaped) area through the front and back of the body. However, round-shaped or irregular patterns also occasionally appear, and this EMF goes through the back and front of the body (or from one side to the other side) when EMF is coming from under the bed or from the wall.

5) Most of the EMF which is creating abnormal imprints on the human body can be detected by the Bi-Digital O-Ring Test. The EMF often cannot be detected by conventional ELF or VLF electric field meters or magnetic field meters within frequency range of 5Hz-400KHz. However this pathogenic EMF often found under the bed is often eliminated by placing aluminum foil or copper sheets over the EMF-emitting area or under the bed, and grounding the metal sheets.

6) Drug uptake in the EMF induced abnormal area is usually almost completely inhibited and no therapeutic dosage can be reached.

7) Acetylcholine is markedly decreased and Thromboxane B2 is increased due to localized micro-circulatory disturbance of EMF exposed pathological areas, while outside of these EMF-induced abnormal areas usually no decrease in Acetylcholine nor increase in Thromboxane B2 exists, unless pathology is present.

8) In electromagnetic field-induced pathological areas, if individuals feel pain or discomfort or have pre-cancer or cancer, in addition to marked decrease in Acetylcholine and appearance of Thromboxane B2, presence of Oncogene C-fos Ab2, Oncogene C-fos Ab1, Integrin 51, and mercury may be found and, and if there is pain, additional Substance P is increased in the painful area.

9) In the electromagnetic field-induced abnormal areas, particularly those due to the very high frequency range of microwaves, areas repeatedly exposed to EMF have markedly increased D-Amino Acids while L-Amino Acids are markedly diminished. For example, L-Glutamic Acid exists in the normal unexposed areas but the presence of D-Glutamic Acid is insignificant L-Phenylalanine is also converted to D-Phenylalnine after exposure to microwaves from a hand- held cellular phone.

Even after only several minutes exposure to microwave EMF's from the hand-held cellular phone, without any obvious side effects, all of the subjects in this study appeared to be more relaxed and showed greater endurance and concentration and also were not disturbed by events which would have irritated the subjects without exposure to these microwaves. This could be due to the increased D-Phenylalanine which inhibits Peptidase activity (the peptidase when uninhibited destroys the activity of -Endorphins). This effect lasts for more than one week.

The sources of these electromagnetic fields which induce the pathological conditions in the patient and create the above characteristics of EMF-induced pathologies are not well known at present. However, the following possibilities exist:

1) The sharp cut surface of metals may function as a kind of antenna and may re-emit strong electromagnetic fields from cut surface areas. Such metal can be a side of a metal plate, which may produce a band-like pathological imprint on the human body, or may be a mental cylinder, which may create a round-shaped abnormality along its axis, or the end of a metal wire of a coiled spring of a bed mattress, particularly if the end of the wire is directed above the horizontal plane of the bed, even when the tip of wire is located several cm below the bed's surface. These metals may be hidden under the floor, bed or within a wall.

2) A deep crack in a large rock under the ground may also function as one unusual type of antenna, particularly if the rock contains metal compounds.

3) A metal water pipe under the floor may create abnormal EMF fields, particularly when the ground current is flowing through the pipe.

4) The electromagnetic fields from an electric wire, microwave or elevators may leak into an uncovered empty space between two metal surfaces.

5) Microwave EMF leaking from a microwave oven within 2 meters.

6) Major subway electric train control stations existing under buildings where individuals have lived for many years.

An example of Item 1 was experimentally shown in our previous publication. In city dwellings, in apartments not close to the ground floor, the possibility of Items 1, 3, 4, 5 are greater than the possibility of Item 2 or 6. We are now in the process of making instruments to scan a broad frequency spectrum to determine the possible causes and frequency components of pathogenic environmental EMF coming from within or under the bed or through the wall.

At all of the abnormal areas at the EMF-exposed entry and exist areas, drug uptake was completely blocked, while the above-described time durations of the EMF-induced abnormal effects remained. Therefore, we speculate that, most likely, in the entire body tissue or parts of the organs existing between the EMF entry and exit areas, drug uptake also is most likely being inhibited. Thus, if someone is taking medication and is exposed to any one of the above mentioned EMF pathogenic influences, the drug effect may either be inhibited or reduced significantly. Therefore, if the patient is being treated with certain medications, the physician should warm the patient that they should not be closer than 3 meters to a television or microwave oven and should warm the patient that they should not be less than 50 centimeters - 1 meter from a computer video display terminal (VDT).

In the case of microwave radiation exposure of the body due to leakage from the microwave oven, in addition to the above described abnormal changes appearing at EMF entry area (usually front) and exist area (usually back) of the body, we found that some microwave cooked food also showed significant abnormal response by the Bi-Digital O-Ring Test immediately after heating while the food is still very hot. For example, when one cup of raw refined white rice with one and one-halt cups of filtered water was well-cooked by gas heat and ready to be eaten, the Bi-Digital O-Ring Test did not show any abnormality, but when the same rice, particularly when the rice was very hot. When hot rice was naturally cooled off by the air in the room, about 20 minutes later the rice in the periphery of the glass pot became almost normal. About one third of the diameter in the central area remained still significantly abnormal, through slightly less abnormal than when immediately pulled out of the microwave oven.

I-2

ELECTRO-MAGNETIC FIELD IN THE HOME ENVIRONMENT (COLOR TV, COMPUTER MONITOR, MICROWAVE OVEN, CELLULAR PHONE, ETC) AS POTENTIAL CONTRIBUTING FACTORS FOR THE INDUCTION OF ONCOGEN C-fos Abl, ONCOGEN C-fos Ab2, INTEGRIN 51 ANDDEVELOPMENT OF CANCER, AS WELL AS EFFECTS OF MICROWAVE ON AMINO ACID COMPOSITION OF FOOD AND LIVEING HUMAN BRAIN

Yoshiaki Omura, M.D, Sc.D., F.A.C.A,F.I.C.A.E. Director of Medical Research, Heart Disease Research Foundation, New York, USA Adjunct Prof., Dept. of Pharmacology, Chicago Medical School, Chicago, USA Visiting Research Prof., Dept. of Electrical Engineering Manhattan College, New York, USA Adjunct Prof., Dept. of Pharmacology, School of Medicine, Showa University, Tokyo, Japan President, International College of Acupuncture and Electro-Therapeutics, New York, USA [Correspondence: 800 Riverside Drive (8-1), new York, NY 10032 USA]

Bro. Michael Losco, M.Sc., F.I.C.A.E., Assistant Prof. Dept. of Electrical Engineering, Manhattan College, New York & Member, Board of Trustees, Heart Disease Research Foundation, New York, USA;

ABSTRACT

The effects, on normal human subjects, of 3 minutes exposure to electromagnetic fields (EMFs) emitted from: A) personal computers, B) color television sets, or C) microwave-ovens, or cellular phones were compared by placing the same large sheet of aluminum foil with a square hole or rectangular band-shaped hole at the chest level (or at the side of head with the cellular phone), with or without grounding the aluminum the foil, using the Bi-Digital O-Ring Test Dysfunction Localization and Molecular Identification Methods with cancer related substances (i.e., Oncogen C-fos Ab2 and mercury in the cell nucleus, Integrin 51 in the cell & nuclear membranes, and disappearance of Acetylcholine) as reference control substances. All the above sources of the EMF not only induced the following various transitional abnormalities at the EMF exist area on the back (where the abnormality was found in the same shape as exposed EMF entry area, and the effect lasted for a shorter time than the entry point of the EMF): A) Exposure of the body at about 50 cm from the monitor of some of the typical personal computers resulted in Al) decrease in Acetylcholine; A2) appearance of circulatory disturbance with the appearance of Thromboxane B2; A3) short-lasting appearance of Oncogen C-fos Ab2; A4)short-lasting appearance of Oncogen C-fos AB1, though it lasted longer than C-fos Ab2; A5) no appearance of Integrin 51. B) part of the chest was exposed at a distance between 1 meter and up to 3 meters from a color television sized anywhere from 13" to 21"resulting in: B1)decrease in Acetylcholine; B2) appearance of circulatory disturbance with the appearance of Thromboxane B2; B3) short-lasting appearance of Oncogen C-fos Ab2;B4) short-lasting appearance of Oncogen Ab1, Though it lasted longer than C-fos Ab2; B5) very short-lasting appearance of Integrin 51. C) When body was exposed, at a distance of 0.5 m-2 meters, to microwaves emitted as leakage from a small microwave oven(about 2.45 GHz with 450 Watt output), the effects usually lasted about 2 to 3 times the exposure time at the exposed area and 1.6 to 2 times the exposure time at the back of the body at the EMF exist area. Immediately after microwave radiation was discontinued, there were the following post-exposure effects expressed in reference to the EMF exposure time: C1) decrease in Acetylcholine (about 2 to 3 times); C2) appearance of circulatory disturbance with the appearance of Thromboxane B2 (about 2 times); C3) short-lasting appearance of Oncogen C-fos Ab2 (sightly shorter than exposure time); C4) short-lasting appearance of Oncogen C-fos Ab1 (close to exposure time); C5) very short-lasting appearance of Integrin 51 (about 1/6 of exposure time). Similar but less effect was found with some hand-held cellular phones (824.030-848.098MHz) placed within 5-10 cm from the human head. When the aluminum foil was grounded, less abnormality appeared even at the exposed part of the chest wall or head in all of the above experiments. This means that prolonged, repeated exposure to EMFs from TV's (about 16 KHz), microwave ovens (2.45GHz), or other similar or higher frequencies without any EMF protection may contribute to the possible development of cancer cells if additional cancer-related virus infection, mercury deposits and other factors coexist, where as EMF from personal computers, such as the Macintosh U(34.9KHz), did not induce Integrin 51 and is therefore less pathogenic than TV. The shape of the area of EMF-induced abnormality at the EMF exit area on the back had a unique pattern characterized by an identical shape corresponding to the shape on the front the EMF entry area on the chest (and vice versa if the entry area was changed from the front to the back). Therefore, if a strong EMF is coming from a band-shaped abnormality in the cross-sectional area through the front and back of the body. Intractable pain or malignant tumors appeared in the cross-sectional areas of 2 or more EMF fields in our clinical cases. When rice with water was cooked or milk was warmed by microwave oven, most of the L-Amino Acids changed to D-Amino Acids. Microwave exposure to the human induced similar amino acid changes. Thus the consumption of microwave-cooked food time may influence the nutritional state of the individual and may contribute to induction of cancer as well as Alzheimers Disease.

Key words: Electrical Filed, Magnetic field, Environmental electro-magnetic field.

I-3

The Paradigm of Biologically Closed Electric Circuits (BCEC) for Structure, Formation and Transition of Matter Into Biological Matter

Bjorn E.W. Nordenstrom, M.D.,F.I.C.A.E. Professor Emeritus, Karolinska Institute, Stockholm, Sweden

Recipient of the Linus Pauling Award 1992 for the Discovery of an Additional Circulation, the Biologically Closed Electric Circuits (BCEC)

ABSTRACT

Electromagnetic energy develops by condensation into non-biological matter (particles). They form atoms and atoms molecules. Biological matter consists basically of equivalent particles (atoms) as non-biological matter derived from the electromagnetic field. Electricity always tends to circulate and preferably in conducting pathways. Man has learned to put function into non-biological matter by guiding electricity in closed circuit cables (lamps, electric tools, etc). Biological matter does contain Biologically Closed Electric Circuits (BCEC-systems) which gradually promote function and structuring of matter into biological matter.

The first recognition of an element of the BCEC-systems was the finding that veins and arteries in the body have their conducting plasma of blood surrounded by relatively insulating vascular walls. Vessels can therefore function as conducting, insulated "cables" which form conductive loops in which current can be induced by external moving electromagnetic fields. The plasma of vessels is electrically connected via leaking capillary walls to the equally conductive interstitial tissue fluid. Thereby is the conducting Vascular-Interstitial Closed Electric Circuits (VICC) formed. They contain equivalents to e.g. biologic capacitors, switching mechanisms and present "electrode" reactions e.g. via redox molecules in cellular membranes.

The working of a muscle produces e.g. lactate and protons. This was identified by "classical chemistry" but unfortunately not followed up. The working muscle becomes electropositive in relation to blood. This leads to electrophoretic transports of degrading products to the blood and the supply of new fuel substances such as sugar and oxygen from the blood to the muscle over the VICC-system. Homeostasis is restored and the muscle can work again. Therefore "classical chemistry" should at least in biology be considered as electrochemistry. All metabolic events and also injury to tissue will start not only "classical chemical" events but also start electrochemical mechanisms such as transports, "signaling" transformation of structures and compounds. Examples will be given of closed circuit transports explaining e.g. the process of healing of a fracture. The driving force of healing is identified as the fluctuating injury potential. It produces of first anodic then cathodic fibrous tissue, the precipitation of Ca ++ Mg ++ leading to callus formation etc. Closely related to the mechanisms of these events are the development of so-called microcalcifications in e.g.breast cancers, which will be described. Explanations will also be made of so-called leukotaxis, chemotaxis, field flow interference, the production of "primitive flakes of tissue", normally recognizable tissue structures such as VICC form also integrated circuits with other conducting media such as ductal contents and the conductive media of nerves. The function of a Vascular-Interstitial-Neuromuscular circuit (VINMC) can in this way be recognized. The existence of these circuit is identified in various ways in animals and man and may replace the common theory of salutatory circuits along the nerves as being energetically impossible. This can relatively easily be checked by identification of activation pulses in associated vessels by muscle contraction. However, a future identification of various compounds such as a possible precursor to acetylcholine in synaptic vesicles, remains to be made. This is a topic of research which is focused on in this conference. The problem of identification of the small amount of vesicular content is one of the important problems the Bi-Digital O-Ring Test hopefully will give us an answer to. Recognition of the extensive network of various BCEC-channels makes it possible to explain many structures and functional events in biology and medicine. It requires knowledge of the basical physics of electricity, which is the dominating mechanism for the development of non-biological matter into biological matter. It is therefore also logical to utilize electricity to modify not only various normal structures but also such as cancer or other disorders in biology. How this is possible will be described in a following presentation.

J-P

HIGH INCIDENCE OF STOMACH CACER DETECTION USING THE BI-DIGITAL O-RING TEST IN COMPARISON WITH STANDARD LABORATORY TESTS

Yasuhiro Shimotuura, M.D.,F.I.C.A.E. Dept. of Medicine, School of Medicine Kurume University, Kurume City, Japan; Director, Dept. of Internal Medicine, St. Mary Hospital Kurume City,Japan;Editor in Chief of Resonance Official Journal of the Japan Bi-Digital O-Ring Test Association. Koichi Ide, M.D.Director, Dept. of Medicine, St.Mary Hospital Kurume City, Japan

ABSTRACT

184 consecutive patients visiting our clinic were examined for adenocarcinoma of the stomach using the Bi-Digital O-Ring Test ,with a microscope slide of adenocarcinoma of the stomach used as a reference control substance ,48(26%)of these patients showed an adenocarcinoma positive response by indirect Bi-Digital O-Ring Test, using a nurse trained in the technique as a 3rd person. All of these 48 individuals were evaluated by standard laboratory tests using x-rays following barium swallowing and gastroscopy, followed by biopsies. 4 of these 48 patients (8.3%) were confirmed to have cancer by standard laboratory tests. Among the patients who had negative Bi-Digital O-Ring Test response to cancer, not a single cancer was detected. Subsequently, another 196 patients visiting the clinic with a variety of medical problems were randomly examined, and the same 196 patient were examined for adenocarcinoma of the stomach once a week for 3 weeks. Only those who consistently indicated adenocarcinoma of the stomach by the Bi-Digital O-Ring Test were given laboratory tests. 21 patients (11%) were adenocarcinoma positive all 3 times to the Bi-Digital O-Ring Test . All of these 21 patients were adenocarcinoma positive all 3 times to the Bi-Digital O-Ring Test. All of these 21 patients were examined by standard laboratory tests, and 5(23.8%) of these 21 were found to have adenocarcinoma of the stomach by standard laboratory tests, consisting of stomach x-rays after barium swallowing and gastroscopy followed by biopsy. This study indicates that the Bi-Digital O-Ring Test cancer screening is simple, safe and highly efficient in its cancer detection and is quick, safe and economical We believe that it will play an important role in future early detection of cancer in the stomach as well as other types of cancer. ACUPUNCTURE & ELECTRO-THERAPEUTICS RES,INT.J,VOL.15,NO,3/4,1990

i|R

SIMPLE NON-INVASIVE EARLY DETECTION AND LOCALIZATION OF SPECIFIC CANCER TISSUES OF INTERNAL ORGANS AND DIFFERENTIATION OF CANCER TISSUE FROM SURROUNDING AREAS INFECTED BY CANCER RELATED VIRUSES, AS WELL AS EVALUATION OF THEIR MICRO-CIRCULATORY CONDITION & DRUG UPTAKE USING THE BI-DIGITAL O-RING TEST

@Yoshiaki Omura, M.D, Sc.D., F.A.C.A,F.I.C.A.E. Director of Medical Research, Heart Disease Research Foundation, New York, USA Adjunct Prof., Dept. of Pharmacology, Chicago Medical School, Chicago, USA Visiting Research Prof., Dept. of Electrical Engineering Manhattan College, New York, USA Adjunct Prof., Dept. of Pharmacology, School of Medicine, Showa University, Tokyo, Japan President, International College of Acupuncture and Electro-Therapeutics, New York, USA [Correspondence: 800 Riverside Drive (8-1), new York, NY 10032 USA]

ABSTRACT

In 1984, the author first developed a simple, quick, non-invasive, economical method of detecting cancer in specific internal organs, using the Bi-Digital O-Ring Test (BDORT), with a microscope slide of specific cancer of a specific internal organ as a reference control substance. The detection rate for cancer screening was much greater than with any standard diagnostic tests. When imaging was performed using the BDORT, the area of positive response to the cancer positive slide was often much greater than the actual size of the cancer itself. This was due to the fact that most of the cancer tissue of the lungs or digestive system contained viruses such as HTLV-3 (often found in adenocarcinoma of the lung, stomach, head of pancreas, and colon) or HTLV-1 (often found in small cell carcinoma of the lung and certain types of leukemia). The extent of the virus positive area was often far greater than that of the cancer tissue itself and was distributed in a much greater area surrounding the cancer. For this reason, the virus alone showed a response which could be mistaken for cancer tissue. The author succeeded in differentiating the exact location of cancer tissue itself from surrounding cancer related virus (with or without other microbes) positive area by using a pair of identical microscope slides with the same cancer tissue. One of the slides was exposed to ultra-violet rays (peak wavelength of 253.7 nm mercury vapor atomic resonance spectral line) for 40 seconds- 4 minutes. After this exposure, the BDORT response to the virus (with or without other microbes) associated with the cancer tissue was completely eliminated while the response to the cancer tissue was maintained. Using an ultraviolet exposed cancer slide, the imaging of the part of the body which responded to this virus-free cancer slide indicated the actual location of the cancer tissue, which was often confirmed by standard X-ray or other imaging methods when the thickness of the tumor was relatively large. These cancer detectable by standard laboratory tests had strikingly weakening response to the BDORT (-3.5 and -4), with ultra-violet exposed cancer slide as well as for antibody of Oncogen C-fos. The smallest size of cancer tissue detected by this method was less than 1mm in diameter in the very early stage of the cancer, which usually cannot be detected by current laboratory tests. The microscope slide of the cancer tissue with surrounding cancer associated viruses showed the extent of the virus infected area to which the cancer might spread in the future. The BDORT often showed that even effective medication did not sufficiently reach the cancer and surrounding cancer-related virus infected area due to a localized micro-circulatory disturbance, detected by an increase in Thromboxane BQ; drug uptake was significantly increased by induced vasodilatation, generally in the following order of effectiveness: positive Qi Gong, acupuncture, transcutaneous electrical stimulation, GEP, calcium channel blocker, or beta-blocker. This simple, non-invasive, early diagnostic method of cancer tissue detection using an ultra-violet exposed microscopic slide or antibody of Oncogen C-fos or other cancer markers can be a very quick economical means of mass screening of the early stage of various cancers of the lung, breast, stomach, colon, head of pancreas, etc.

Key WordsFEarly detection of cancer, Cancer associated viruses, HTLV-3, HTLV-1, Adenocarcinoma (of the lung, colon, stomach, head of the pancreas), Small cell carcinoma of the Lung, Breast cancer, Ultraviolet radiation, Destruction of viruses and other microbes, Bi-Digital O-Ring Test, Antibody of Oncogen C-fos, Anti-viral agents, Anti-cancer agents, EPA (Eicosa Penta-Enoic Acid), Thoromboxane BQ, Microcirculatory disturbance, Vasodilators, Qi Gong. Microscopic intracellular Bi-Digital O-Ring Test

J-4

Electrochemical Treatment of Cancer (ECT)

Bjorn E.W. Nordenstrom, M.D.,F.I.C.A.E. Professor Emeritus, Karolinska Institute, Stockholm, Sweden

ABSTRACT

The Biologically Closed Circuits in the body form multiple systems for the flow of ions. The first recognition of structural changes in tissue produced by a flow of current through the VICC-channels was made around cancers of the lung when the tumors necrotized centrally. In radiographs as many as 13 structural modifications could be described. They were called the corona structures represent the result of a partial healing of the cancer due to the liberation of electrochemical energy at the in this case central degradation of cancer tissue. It was then thought that a further supply of electric energy with flow of current between inserted electrodes should increase the structural modifications and enhance the healing. A first test to activate the VICC system artificially was therefore tested which also showed the induction of the healing of cancers. The most important mechanisms of these electrochemical treatments will be summarized when practiced in the lung. The diagnosis of cancer is often made by needle biopsy which requires equipment for precise localization of the instrument. Similar precision is used at the implantation of one electrode in the center of the tumor and one in the surrounding tissue. In order to prevent a collapse of the lung by pneumothorax in treating lung cancer, suction is usually applied to a draining tube introduced into the pleura. When 10 volts of DC is applied between the electrodes and the tumor is made anodic, several electrochemical events occur. Around the anode, H+ ions are produced which drives the pH down to about 2. When protons migrate and diffuse around the anode the affected cancer tissue will be destroyed. Centrally, chlorine gas will bleach the destroyed tumor. Also oxygen gas is evolved. Around the cathode, pH will be about 12 because OH-ions and hydrogen gas will evolve. Tissue water moves by electroosmosis from the anodic to the cathodic tissue. Besides these changes also many other changes will occur in the electric field between the electrodes. Thus, multiple microthrombosises will occur in capillaries around the anode while many vessels are mechanically blockedby increased turgor pressure around the cathode. Effects on the immune system is observed. White blood cells which are electronegatively charged are accumulated in enormous amounts in the tissues around the anode. Small islands of cancer cells are also destroyed by the distortion of ionic concentrations in the field or by direct effects on intracellular ions by the circulating field. A series of treatment effects are demonstrated in patients when standard treatments of the cancers were rejected. In this way up to 15 years of cure of otherwise incurable anti-cancerous chemical agents. Intravenous injection of electropositive Adriamycin will accumulate in high concentration in the tumor region with lowered systemic effects.By injection of this agent into a hollow anode, it will spread in a high concentration around the anode. In a corresponding way also an electronegative chemical can be used or even simultaneously both an electronegative and an electropositive compound. After the introduction of ECT in Beijing, China in 1987, the thoracic surgeon, Professor Xin Yu-Ling adapted the technique. He and his coworkers had in October1992 performed 3,200 treatments in 416 hospitals with about 79% complete initial regression. Their 4 year results showed permanent regression in almost 60% of the cases. These results are remarkable. On September 12-15 this year we will have a conference in Stockholm, Sweden of the International Association of Biologically Closed Electric Circuits in Biomedicine(IABC). The main topic will be Electrochemical Treatment of Cancer and the Chinese colleagues will present their material. Also other methods for influencing medical disorders via the BCEC-systems will be presented. Information about participation in the IABC Conference can be made by contacting me or Congress (Sweden) AB, Attn: IABC-93, P.O. Box 5619, S-114 86 Stockholm, Sweden. Tel# +46 8 612 69 00, Fax# +46 8 612 62 92.

L-1

THE EFFECT OF PROTOPAM CHLORIDE ON ABNORMAL NEUROLOGICAL FUNCTION IN PATIENTS WITH MULTIPLE SCLEROSIS

Albert W. Cook, M.D., F.I.C.A.E. Professor of Neurosurgery, Emeritus, & Former Chairman, Dept. of Neurosurgery, State University of New York, Downstate Medical Center, Brooklyn, New York

ABSTRACT

In the center of Plaques in the central nervous system of patients with Multiple Sclerosis examined at autopsy, there is a selective marked decrease in Pseudo Cholinesterase. The cause of this abnormality is unknown. Empirically, a cholinesterase reactivator, 2 Pam Chloride, was administered because of the biochemical abnormality.

A video demonstration will indicate the transitional striking beneficial effect of this procedure.

The Bi-Digital O-Ring Test is capable of monitoring these effects.

L-2

EFFECT OF ELECTRICAL STIMULATION, QI GONG OR 60HZ ELECTRICAL FIELD ON ACETYLCHOLINE & CIRCULATION OF EXPOSED PARTS OF THE BODY, AS WELL AS ON INSOMNIA & SHORT TERM MEMORY, AND EVALUATION & TREATMENT OF ALZHEIMER'S DISEASE BY THE USE OF THE BI-DIGITAL O-RING TEST

Yoshiaki Omura, M.D, Sc.D., F.A.C.A,F.I.C.A.E. Director of Medical Research, Heart Disease Research Foundation, New York, USA Adjunct Prof., Dept. of Pharmacology, Chicago Medical School, Chicago, USA Visiting Research Prof., Dept. of Electrical Engineering Manhattan College, New York, USA Adjunct Prof., Dept. of Pharmacology, School of Medicine, Showa University, Tokyo, Japan President, International College of Acupuncture and Electro-Therapeutics, New York, USA [Correspondence: 800 Riverside Drive (8-1), new York, NY 10032 USA]

ABSTRACT

Although no effective treatment is known for Alzheimer's disease, the author has found that application of either acupuncture, (+) Qi Gong energy stored paper or extremely low pulse repetition rate electrical stimulation of 1-2 pulses/sec at the occipital area above the medulla oblongata, where a cardiovascular representation area exists, and the vertebral artery at the back of the neck, along with administration of EPA with DHA as effective anti-viral agent and an anti-bacterial agent, such as amoxicillin (if bacterial infection co-exists in the brain), not only eliminates circulatory disturbance, with disappearance of Thromboxance B2, but also increases acetylcholine in the hippocampal area and the rest of the brain, with frequent improvement in short-term memory, as long as acetylcholine reappears in the hippocampal area where acetylcholine is markedly diminished or can't be detected. All the 5 Alzheimer's patients examined had 1) circulatory disturbance and 2) disappearance of acetylcholine, with 3) heavy metal deposits and 4) subclinical multiple viral infection, with or without subclinical bacterial infection. Three patients had various degrees of transitional improvement (about 4 hours) with application of (+) Qi Gong energy stored paper alone. However, when transcranial electrical stimulation of 1-2pulses/sec was given through a pair of surface electrodes with electro-conductive jelly, the effect often lasted much longer, with better results. When an electric wire or electric appliance, such as an electric lamp or clock, is located within 30 cm, even if the switch is off and no current is flowing, if it is plugged into the wall socket, there is often an electrical field of more than 20 V/m. Our study indicated that, if there is an electrical field of more than 10 V/m, acetylcholine becomes significantly reduced in the part of the body exposed to such a field, along with circulatory disturbance. If this happens in the brain during the night, insomnia or reversible transitional short-term memory disturbance often develops. Such a disturbance usually lasts for about the same time duration as exposure time to the field. Frequent prolonged exposure to 50-60 Hz electrical fields may contribute to or enhance Alzheimer's disease, as well as creating short-term memory disturbance and/or insomnia. However, if additional heavy metal deposits and viral infection co-exist, electrical fields become significant contributing factors to chronic intractable medical problems.

M-1

CLINICAL APPLICATIONS OF THE BI-DIGITAL O-RING TEST

Pekka J. Pontinen, M.D., Ph.D., F.I.C.I.E., F.A.A.A., F.A.C.A.Assoc. Prof. of Anesthesiology, Tampere University; Consultant, Dept. of Neurology, Tampere University Hospital; Lecturer, Institute for Extension Studies, Tampere University; Tampere, Finland. Assoc. Prof. of Anesthesiology, Kuopio University; Director, Acupuncture Research Project, Institute of Physiology, Kuopio University, Kuopio, Finland. Former Medical Director, Kankaanpaa Rehabilitation Center, Kankaanpaa, Finland. Editor-in-Chief, Scandinavian Journal of Acupuncture & Electrotherapy; Editor, Acupuncture & Electro-Therapeutics Research, the International Journal; Editor, AKU, Akupunktur-Theorie und Praxis.

Abstract

Since introduction of Bi-Digital O-Ring Test by Omura (1-3) we have studied its possible applications in clinical practice for better diagnostics and therapy mainly in pain clinic population and in respiratory diseases (4-6, 10-13). This report is a review of our experience covering a ten year period. Local tenderness near the midline either in front or in the back of the body is a typical phenomenon in many musculoskeletal pain syndromes and in functional disorders of the gastrointestinal or respiratory tracts. These tender areas correspond well with the organ representation points in Oriental Medicine. There are also close links between organ representation points and corresponding channel points. Trigger points and their referred pain zones are Western counterparts to this phenomenon. Sensory irritation of these tender zones may markedly reduce muscle force throughout the striated musculature. A simple method to check the organ involved in the abnormal response (8). The same method can be applied as a food and drug compatibility test (1,6,11). In our clinical praxis we use Bi-Digital O-Ring Test mainly in following condition:

(1) An overall screening test of the immune system (thymus representation area);

(2) to locate the abnormal segment in vertebrogenic problems, e.g. in cervico-brachialgias and ischialgias;

(3) to map the area of abnormal sensory/motor function;

(4) to map the area of abnormal circulation, e.g. in hemicrania;

(5) to check the type of tissue involved in the abnormal response, e.g. n. ischiadicus for peripheral referred pain zone in ischialgia;

(6) as a food and drug compatibility test, e.g. in allergic versus infectious rhinitis.

M-2

MY PATH TO THE BI-DIGITAL O-RING TEST

Soren Jorgensen, M.D. Prof. & Former Chairman, Dept. of Anaesthesiology, Odense University, Odense, Denmark

ABSTRACT

A brief summary is given a Danish anesthesiologist's disappointing experience throughout many decades with the so-called blockade treatment using local anesthetics in the treatment of chronic pain. This was followed by a gradual transition to the use of acupuncture after much hesitation in both hospital work and in private practice. Acupuncture carried out single handed in a hospital when surrounded, at least at the start, by colleagues shaking their heads, was very instructive, but did not permit of any research. However, increasing experience throughout a period of more than ten years of clinical work together with 3 to 4 years of study and continued clinical work, have shown the results of treatment are of such a character that they are of great value to a vast majority of patients. Throughout the last 2 years, the Bi-Digital O-Ring Test, employing in the main, the indirected method, has been used for diagnostic purposes and as a standard procedure together with my general medical judgement for evaluating the results of treatment. Practical examples will be demonstrated with the help of slides. Almost all of our patients had been treated by their own physician, and frequently also by various specialists before being referred to our clinic. We are able to improve the lot of more than one half of our patients. Should we be unable to do using these physicians. If the condition is not improved then it may be the physician who is at fault, not the patient.

The instruction of senior medical students will be mentioned.

The Bi-Digital O-Ring Test is in my opinion a method of examination which is just as valid as testing tendon reflexes. However, Western Science (and the Japanese) will demand parameters which can be repeated and reproduced. The fact remains that those of us who are convinced of the method's efficacy must find more exact measures of the method in order to overcome the general skepticism.

Questions will be asked as to the nature of the method and its reliability.

M-3

HETEROGENITY OF PAIN PEPTIDE MECHANISMS AND INDICIDUAL PROPERTIES. POTENTIAL USE OF THE O-RING TEST IN PAIN PHYSIOLOGY

Kalyuzhnyi L.,M.D.,Sc.D., Fedoseeva O., Raevskaya O., Institute of Normal Physiology of Russian Academy of Medical Sciences

ABSTRACT

Pain threshold is determined by genetic interaction of endogenous nociceptive and antinociceptive neurochemical mechanisms and in particularly peptide mechanisms which are different at the pain of various origin. The main goal of pain physiology is to search the most effective antinociceptive peptides for the treatment of the pain syndrome in depend on the origin. For example, it was shown the preference of delta-agonist in thermal pain and kappa-agonist in chemical pain (Yaksh T., 1980). In our experimental researches it has been established that neurotropin is more effective for thermal pain electrocutaneous pain but not for dental pain. Angiotensin II is more effective for dental pain but not for electrocutaneous one. For to receive these results we used some tests and some different drugs with the blind puzzles of choice. One can think that the use of O-Ring test it would be possible to define the perspective drugs beforehand for the choice of research ways. Besides as it has been established there are some lines of animals who have different endogenous opioid deficit and can not react to it. Moreover our researches were shown that there are individual beings who doesn't react for different drugs. For example, 30% of Wistar rats and rabbits are morphine-insensitive. They didn't react also in response to acupuncture stimulation which induced the activation of endogenous opioid system, but they reacted in response to acupuncture which induced the activation of endogenous angiotensinergic mechanism and vice versa. One can think that the O-Ring test will help to define the animal's individual properties and perspective peptide mechanisms for antinociception for these ones. However a pain physiology requires the objective estimation for using method and for O-Ring test there is the necessity to have the electronic estimation of the power of the ring press and the power of the unclasp.

M-4

Usual and Unusual Diagnostic and Therapy of Chronic Pain In Germany; Use of Bi-Digital O-Ring Test

Thomas Floter M.D.,FICAE ;President, Schmerz-Therapeutisches Kolloquim, and Pain Treatment Center of Frankfurt, Germany

ABSTRACT

The care of chronic pain patients in Germany is still Incomplete. Out of approximately six million chronic pain patient 600 thousand require a special algesiologic treatment. 1500 pain centers are necessary for these patients, although there are only 150 in existence. The most significant reasons for the low level of care are lacking appreciation of the problem, lacking further education, confusion over acute and chronic pain, improper use of the information available, deficiencies in research, and restrictive legislation (Health System Structure Reform Law and Drug Law). The SCHMERZ Therapeutisches Kolloquium (Pain Forum), which has over 2000 members, has achieved pioneering work for 10 years: definition of the algesiologist and implementation of the necessary further education. The diagnostic and therapeutic spectrum of pain therapy is wide, there are common and uncommon methods of treatment. The usual clinical diagnosis is completed first of all with diagnostics using the five senses; the measurement of pain is too detailed for the everyday clinic. Algopressuremetrics and psychological methods of testing (visual analogue scales and psychometric tastes) have proved useful. Still unusual, though firmly integrated into our work, is the diagnostic investigation with the Bi-Digital O-Ring Test. Since 1984 we held a dozen courses with Prof. Omura and Prof. Pontinen, and trained several hundred participants of these courses. We use this simple kind of test to measure and localize pain and for therapy control. The Bi-Digital O-Ring Test also proved highly useful in the testing of pharmaceuticals: selection of the medication, establishing of dose, and tolerance tests. We also test foodstuffs within the framework of establishing an pain relieving alimentation program. In connection with this special diet it proved useful to train the patients and their family in the handling of this test. The Bi-Digital O-Ring Test is highly reliable in the case of food intolerance and allergies to foodstuffs. The limits of such a sensitive test are soon reached if positive findings are misinterpreted, e,d, it would be fatal to infer a clinically manifest carcinoma disease from the finding of individual carcinoma cells. The Bi-Digital O-Ring test in non-invasive, harmless and also lower priced than many other diagnostic methods. In our experience with many hundred patients the Bi-Digital O-Ring Test means a useful complement to the diagnostic methods of traditional medicine if it is used properly and with an eye to reality. Electric test devices, though being more impressive for patients, seem to be inferior to the Bi-Digital O-Ring test as concerns accuracy and reproducibility of the results. We only want to briefly enumerate the therapeutic methods used and approved of in Germany: pharmacotherapy, neural blockade, physical therapy, mutual therapy, acupuncture, transcutaneous electric nerve stimulation, laser, psychotherapy, peridural application of opiates, pain surgery, neurolytical nerve blocks. Unusual, though proven, tried and tested in practice, are the following methods, e.d.: cupping, cantharidin plaster, Baunscheidt's airpuncture treatment subcutaneous CO2-insufflation, spiritual healing, homeopathy, anthroposophy, reflexotherapy, phytotherapy, chiropodology, pain-relieving nutrition. We want to take a closer look at pharmacotherapy, because a new study is to be presented. In drug therapy we are have to combat ignorance, prejudice and restricting statutory regulations. According to popular medical opinion the opiates should only be given to terminal cancer patients. The reality, however, is that there are many conditions of pain which can be controlled only with the opiates. In order to reduce ignorance and prejudices we performed a retrospective study investigating the effectiveness and compatibility of centrally acting analgesics in long-term therapy. Special regard was directed towards compliance, patient condition and adverse effects. Analyzed were the data of 412 patients, average age 64 years. The majority of the patients suffocate from pain of non malignant origin (e.g. arthroses, stump and phantom pain, neuralgias). The average therapy lasted for half a year, compatibility was very good, regularly reported was only constipation due to morphine. None of the patients developed dependency or addiction. The doses established for the different opiates were tested with the Bi-Digital O-Ring Test. Chronic pain often needs to be treated continually for years with potent and most potent analgesics; complementary pain therapy procedures should supplement therapy.

M-5

ENDORPHINS AS PUTATIVE MEDIATORS OF THE MULTIFACETED PHYSIOLOGICAL AND THEREAPUTIC EFFECTS OF ACUPUNCTURE

Saymour Ehrenpreis, Ph.D. Department of Pharmacology and Molecular Biology and Medicine, Chicago Medical School, North Chicago, IL, USA 60064-3095

ABSTRACT

Acupuncture produces a great variety of beneficial effects on the body, most notably in counteracting painful conditions. Other actions include; Anti-inflammatory, vasodilation (hypotension), anti-convulsant, anti-depression, anti-psychotic, anti-compulsive behavior (smoking, drug and alcohol addiction, overeating), induction of sleep, activation of the immune system. The following lines of evidence support the hypothesis that many of these effects can be accounted for on the basis of established biochemical, physiological and anatomical mechanisms and that the ultimate mediators of such actions are one or more endorphins:

1. Many of the actions produced by acupuncture can be mimicked by one or more endorphins given exogenously to animals and humans.

2. It can be shown that endorphins are mobilized by acupuncture and that levels increase in the CSF and brain in parallel with acupuncture action.

3. Many aspects of acupuncture action can be contracted or blocked by potent, specific endorphin antagonists, e.g. naloxone, or by endorphin antibodies administered to specific brain regions.

4. Enkephalinase inhibitors, introduced by the author and his colleagues, can greatly enhance the effectiveness of acupuncture, improve the reliability of acupuncture analgesia in animals and humans, and alone can produce many of acupuncture's effects.

5. Takeshige and colleagues have carried out extensive studies which establish the fact that acupuncture stimuli travel over discrete neuronal pathways.

Thus it is postulated that since many of acupuncture's actions can be modified in a predictable manner in a variety of ways strongly suggests that specific biochemical/physiological mechanisms are involved. The demonstration that many of the actions of acupuncture can be mimicked by one or more endorphins, plus the fact that endogenous endorphin levels are markedly increased during acupuncture, leads to the conclusion that the stimuli initiated by acupuncture travel overdiscreteneuronal pathways and ultimately mobilize and release one or more endorphins, the mediators of many, if not all, the actions of acupuncture. Possible roles of endorphins as mediators of the Bi-Digital O-Ring Test will also be discussed.

N-1

TMJ AND ACUPUNCTURE

Joel Friedman, D.D.S., F.I.C.A.E.Prof., New York University Dental School, New York, U.S.A.; Vice President, International Council for the International College of Acupuncture and Electro-Therapeutics

ABSTRACT
T.M.Joint
Bones
Temporal - mandibular fofssa
Mandible - condylar head

Disc:
Fibrocartilage, between the bones.
Upper plane joint space and lower hinge joint space.
The joint is a synovial joint.
It is also a ginglymo-arthrodial joint, which is hinge-sliding.
Ligaments
Capsule of joint
Stylomandibular ligament
Sphenomandibular ligament
Lateral collateral ligament
Muscles
Temporalis
Masseter
Medial pterygoid
Lateral pterygoid
Vascular supply
Superficial temporal artery
Maxillary artery
Posterior deep temporal artery
Masseteric artery
Innervation
Auriculotemporal nerve (posterior part of TMJ)
Masseteric nerve
Diagnosis
Bi-Digital O-Ring Testing
Pain as the presenting symptonm
Restricted opening
Subluxations
Therapy
Splints
Stabilization
Repositioning
Acupuncture needling
Electro-therapeutics with TENS

N-3

Application of Bi-Digital O-Ring Test (ORT) in Dental Practice

Akira Fukuoka, D.D.S, Ph.D. President of Meitokukai Fukuoka Dental Clinic Research Laboratory of Oriental Medicine

ABSTRACT

As the result of groping of clinical application of Bi-Digital O-Ring Test in dental practice, this technique was found to be useful for the following matters:

1. Determination of an affected tooth at the time of failure of causative tooth identification.

2. Confirmation of affected and inflammatory lesions of dental diseased and examination of their subsequent courses.

3. Estimation of drug compatibility and optimal dose.

4. Aids for identification of causative organisms, selection of antibiotics, and confirmation of penetration of drugs into lesions.

5. Determination of therapeutic points of toothache, trigeminal neuralgia, facial palsy, arthritis of the temporomandibular joint, etc.

6. Imaging of the region of pain or paralysis, such as trigeminal neuralgia,facial palsy, inferior alveolar nerve paralysis, and glossalgia.

7. Index for the determination of mandibular position (vertical dimension and horizontal mandibular position).

8. Index for the diagnosis of intraoral tumor.

9. Understanding of physical conditions of patients.

10. Index for the determination of immunity and stress.

11. Index for the understanding of acupuncture points related to other oral diseases (stimulation of Source points and Terminal points)and selection of indicated acupuncture points.

This time a few methodology on these matters will be described.

N-4

EVALUATION OF INTRACTABLE FACIAL OR DENTAL PAIN AND TEMPORO-MANDIBULAR JOINT (TMJ) PROBLEMS, USING BI-DIGITAL O-RING TEST IMAGING OF EACH COMPONENT OF THE TMJ AT CLOSURE & OPENING OF THE MOUTH, & GENERAL CONDITION OF THE PATIENT BY TONGUE DIAGNOSIS

Yoshiaki Omura, M.D, Sc.D., F.A.C.A,F.I.C.A.E. Director of Medical Research, Heart Disease Research Foundation, New York, USA Adjunct Prof., Dept. of Pharmacology, Chicago Medical School, Chicago, USA Visiting Research Prof., Dept. of Electrical Engineering Manhattan College, New York, USA Adjunct Prof., Dept. of Pharmacology, School of Medicine, Showa University, Tokyo, Japan President, International College of Acupuncture and Electro-Therapeutics, New York, USA [Correspondence: 800 Riverside Drive (8-1), new York, NY 10032 USA]

Abstract

When the patient has intractable pain associated with a dental procedure, the most common cause was found to be Herpes simplex typeTinfection, particularly pain existing on one side, and the pain did not disappear even if all the teeth were removed by dentists. According to the Bi-Digital O-Ring Test, the most effective treatment was found to be EPA with DHA, but the medication usually never reached the infected area in sufficient amounts. As a result, there was no improvement. However, the authors discovered several methods of drug uptake enhancement, including 1)acupuncture, 2)extremely low pulse repetition rate transcutaneous electrical stimulation (1-2 pulses/sec), 3)(-)electrical field, 4)soft laser of red spectrum or near infra-red, 5)(+)Qi Gong energy stored paper, etc. By giving EPA and DHA and enhancing drug uptake by application of (+)Qi Gong energy stored paper, most intractable pain with a history of many years disappeared within 1-3 weeks. The second most common cause of facial or dental pain was Alpha-Streptococcus infection, which has the same problem of markedly reduced drug uptake and becomes intractable pain. For this infection, oral Amoxicillin with application of (+)Qi Gong energy stored paper or other drug uptake enhancement methods resulted in rapid improvement of intractable pain and disappearance of Alpha Streptococcus infection.

Typical temporo-mandibular joint problems have the following triad: 1) Limitation of opening of the mouth. 2) Clicking sound from TMJ upon opening the mouth. 3) Pain at the TMJ upon opening the mouth. However, TMJ problems often exist without the typical triad being present.

Using simple Bi-Digital O-Ring Test evaluation of the TMJ with the mouth closed (with or without biting plastic sheets of various thickness) or with the mouth open provides a quick means of diagnosing TMJ problems, even if typical symptoms are not present. In order to determine the exact location and nature of the TMJ problems, we image and map the outline of the major components of TMJ (upper joint cavity, including Mandibular fossa and articular tubercule of the Temporal bone; lower joint cavity, including Capsuleand Condyle of mandibular bone; articular disk between upper and lower TMJ cavities; Capsular ligament and lateral ligament forming the TMJ side wall), while the mouth is closed and while the mouth is open. To do such imaging, we obtained small pieces of tissue from human cadavers: 1) part of the mandibular fossa; 2) part of the articular disk; 3) part of the condyle.

Each part of the TMJ joint was either dried or put into formaldehyde in small plastic sample containers of 1 cc capacity and closed with a cover cap. Using one of these components as a reference control substance, corresponding outlines of the TMJ were imaged on the skin covering the TMJ while the mouth was closed as well as while the mouth was open. At the imaged part of the TMJ at both the mouth closed and mouth open position, each abnormality was detected and mapped on the exact anatomical location on the imaged TMJ. TMJ problems can often be improved by transcutaneous electrical stimulation (1-2 pulses/sec) alone in the absence of infection, and can also be improved by effective anti-bacterial or anti-viral agents along with (+) Qi Gong energy stored paper, or by other drug uptake enhancement methods if infection exists. Using the accurate organ representation area map of the tongue localized by the Bi-Digital O-Ring Test, it is possible to quickly estimate abnormal condition of different internal organs of the patient by observation of the tongue alone during oral examination.